Ischemic heart disease pathophysiology paradigms overview: from plaque activation to microvascular dysfunction

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Ischemic heart disease and heart failure: role of coronary ion channels

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Heart failure is a complex syndrome responsible for high rates of death and hospitalization.
Ischemic heart disease is one of the most frequent causes of heart failure and it is normally …

A statement of the MDS on biological definition, staging, and classification of Parkinson's disease

F Cardoso, CG Goetz, TA Mestre… - Movement …, 2024 - Wiley Online Library
Disease staging is an important tool in both clinical research and medical practice because
it allows for an unequivocal allocation of individuals into groups of shared biomedical …

The Effect of the Teach‐Back Method on Knowledge, Performance, Readmission, and Quality of Life in Heart Failure Patients

A Rahmani, A Vahedian-Azimi… - Cardiology research …, 2020 - Wiley Online Library
Background. Among chronic diseases, heart failure has always been a serious challenge
imposing high costs on health systems and societies. Therefore, nurses should adopt new …

Heart failure pharmacological management: gaps and current perspectives

P Severino, A D'Amato, S Prosperi, V Myftari… - Journal of clinical …, 2023 - mdpi.com
Proper therapeutic management of patients with heart failure (HF) is a major challenge for
cardiologists. Current guidelines indicate to start therapy with angiotensin converting …

Induced pluripotent stem cell-derived cardiomyocytes therapy for ischemic heart disease in animal model: A meta-analysis

QD Vo, Y Saito, K Nakamura, T Iida… - International journal of …, 2024 - mdpi.com
Ischemic heart disease (IHD) poses a significant challenge in cardiovascular health, with
current treatments showing limited success. Induced pluripotent derived–cardiomyocyte …

Reduction in heart failure hospitalization rate during coronavirus disease 19 pandemic outbreak

P Severino, A D'Amato, A Saglietto… - ESC Heart …, 2020 - Wiley Online Library
Aims The recent coronavirus disease 19 (COVID‐19) pandemic outbreak forced the
adoption of restraint measures, which modified the hospital admission patterns for several …

Do the current guidelines for heart failure diagnosis and treatment fit with clinical complexity?

P Severino, A D'Amato, S Prosperi, A Dei Cas… - Journal of Clinical …, 2022 - mdpi.com
Heart failure (HF) is a clinical syndrome defined by specific symptoms and signs due to
structural and/or functional heart abnormalities, which lead to inadequate cardiac output …

Myocardial tissue characterization in heart failure with preserved ejection fraction: from histopathology and cardiac magnetic resonance findings to therapeutic targets

P Severino, A D'Amato, S Prosperi, F Fanisio… - International Journal of …, 2021 - mdpi.com
Heart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome
responsible for high mortality and morbidity rates. It has an ever growing social and …

Fluid–structure interaction modelling of a positive-displacement Total Artificial Heart

J Bornoff, A Najar, L Fresiello, T Finocchiaro… - Scientific reports, 2023 - nature.com
For those suffering from end-stage biventricular heart failure, and where a heart
transplantation is not a viable option, a Total Artificial Heart (TAH) can be used as a bridge to …