[HTML][HTML] NY-ESO-1 based immunotherapy of cancer: current perspectives
R Thomas, G Al-Khadairi, J Roelands… - Frontiers in …, 2018 - frontiersin.org
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-
testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit …
testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit …
Everything You Ever Wanted to Know About Saccharomyces cerevisiae Telomeres: Beginning to End
RJ Wellinger, VA Zakian - Genetics, 2012 - academic.oup.com
The mechanisms that maintain the stability of chromosome ends have broad impact on
genome integrity in all eukaryotes. Budding yeast is a premier organism for telomere …
genome integrity in all eukaryotes. Budding yeast is a premier organism for telomere …
Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly
Galloway–Mowat syndrome (GAMOS) is an autosomal-recessive disease characterized by
the combination of early-onset nephrotic syndrome (SRNS) and microcephaly with brain …
the combination of early-onset nephrotic syndrome (SRNS) and microcephaly with brain …
[HTML][HTML] Evolution of cancer vaccines—Challenges, achievements, and future directions
The development of cancer vaccines has been intensively pursued over the past 50 years
with modest success. However, recent advancements in the fields of genetics, molecular …
with modest success. However, recent advancements in the fields of genetics, molecular …
[HTML][HTML] Bispecific antibodies for multiple myeloma: a review of targets, drugs, clinical trials, and future directions
C Caraccio, S Krishna, DJ Phillips… - Frontiers in …, 2020 - frontiersin.org
Multiple myeloma (MM) is a plasma cell malignancy and the second most common
hematological neoplasm in adults, comprising 1.8% of all cancers. With an annual incidence …
hematological neoplasm in adults, comprising 1.8% of all cancers. With an annual incidence …
[PDF][PDF] Transcriptome-wide analysis of roles for tRNA modifications in translational regulation
Covalent nucleotide modifications in noncoding RNAs affect a plethora of biological
processes, and new functions continue to be discovered even for well-known modifying …
processes, and new functions continue to be discovered even for well-known modifying …
Monothiol glutaredoxins: a common domain for multiple functions
E Herrero, MA de la Torre-Ruiz - Cellular and molecular life sciences, 2007 - Springer
Monothiol glutaredoxins with the CGFS sequence at the active site are widespread among
prokaryotes and eukaryotes. Two subclasses exist, those with a single glutaredoxin domain …
prokaryotes and eukaryotes. Two subclasses exist, those with a single glutaredoxin domain …
The highly conserved KEOPS/EKC complex is essential for a universal tRNA modification, t6A
The highly conserved Kinase, Endopeptidase and Other Proteins of small Size (KEOPS)/
Endopeptidase‐like and Kinase associated to transcribed Chromatin (EKC) protein complex …
Endopeptidase‐like and Kinase associated to transcribed Chromatin (EKC) protein complex …
[HTML][HTML] Defects in t6A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome
C Arrondel, S Missoury, R Snoek, J Patat… - Nature …, 2019 - nature.com
N6-threonyl-carbamoylation of adenosine 37 of ANN-type tRNAs (t6A) is a universal
modification essential for translational accuracy and efficiency. The t6A pathway uses two …
modification essential for translational accuracy and efficiency. The t6A pathway uses two …
The structural and functional workings of KEOPS
J Beenstock, F Sicheri - Nucleic Acids Research, 2021 - academic.oup.com
Abstract KEOPS (K inase, E ndopeptidase and O ther P roteins of S mall size) is a five-
subunit protein complex that is highly conserved in eukaryotes and archaea and is essential …
subunit protein complex that is highly conserved in eukaryotes and archaea and is essential …