Discontinuation, suboptimal adherence, and reinitiation of oral HIV pre-exposure prophylaxis: a global systematic review and meta-analysis

J Zhang, C Li, J Xu, Z Hu, SE Rutstein, JD Tucker… - The lancet HIV, 2022 - thelancet.com
Background Poor adherence to oral HIV pre-exposure prophylaxis (PrEP) diminishes its
clinical and public health benefits. This study synthesises evidence regarding …

PrEP rollout in Africa: status and opportunity

EM Irungu, JM Baeten - Nature medicine, 2020 - nature.com
Following recommendations by the World Health Organization in 2015, and key clinical
trials, countries in sub-Saharan Africa, the region with the highest burden of human …

Artificial intelligence and machine learning for HIV prevention: emerging approaches to ending the epidemic

JL Marcus, WC Sewell, LB Balzer… - Current HIV/AIDS …, 2020 - Springer
Abstract Purpose of Review We review applications of artificial intelligence (AI), including
machine learning (ML), in the field of HIV prevention. Recent Findings ML approaches have …

[HTML][HTML] Cost-effectiveness of easy-access, risk-informed oral pre-exposure prophylaxis in HIV epidemics in sub-Saharan Africa: a modelling study

AN Phillips, A Bershteyn, P Revill, L Bansi-Matharu… - The Lancet …, 2022 - thelancet.com
Background Approaches that allow easy access to pre-exposure prophylaxis (PrEP), such
as over-the-counter provision at pharmacies, could facilitate risk-informed PrEP use and …

[HTML][HTML] HIV incidence after pre-exposure prophylaxis initiation among women and men at elevated HIV risk: a population-based study in rural Kenya and Uganda

CA Koss, DV Havlir, J Ayieko, D Kwarisiima… - PLoS …, 2021 - journals.plos.org
Background Oral pre-exposure prophylaxis (PrEP) is highly effective for HIV prevention, but
data are limited on HIV incidence among PrEP users in generalized epidemic settings …

Using a HIV prevention cascade for identifying missed opportunities in PrEP delivery in Kenya: results from a programmatic surveillance study

D Were, A Musau, J Mutegi, P Ongwen… - Journal of the …, 2020 - Wiley Online Library
Introduction HIV prevention cascades have been systematically evaluated in high‐income
countries, but steps in the pre‐exposure prophylaxis (PrEP) service delivery cascade have …

HIV prevention: better choice for better coverage

LG Bekker, C Pike, SL Hillier - African Journal of Reproduction …, 2022 - journals.lww.com
Introduction: Antiretroviral-based pre-exposure prophylaxis (PrEP) is today an established,
effective and safe method of HIV prevention used in multiple countries worldwide by a broad …

Service delivery models that promote linkages to PrEP for adolescent girls and young women and men in sub-Saharan Africa: a scoping review

T Ramraj, W Chirinda, K Jonas, D Govindasamy… - BMJ open, 2023 - bmjopen.bmj.com
Background Pre-exposure prophylaxis (PrEP) is an emerging biomedical prevention
intervention. Documenting PrEP service delivery models (SDMs) that promote linkage to and …

Oral pre‐exposure prophylaxis preference, uptake, adherence and continuation among adolescent girls and young women in Kampala, Uganda: a prospective cohort …

Y Mayanja, O Kamacooko, JF Lunkuse… - Journal of the …, 2022 - Wiley Online Library
Introduction Oral pre‐exposure prophylaxis (PrEP) has been scaled up; however, data from
real‐world settings are limited. We studied oral PrEP preference, uptake, adherence and …

[HTML][HTML] Integration of pre-exposure prophylaxis services into public HIV care clinics in Kenya: a pragmatic stepped-wedge randomised trial

EM Irungu, KK Mugwanya, NR Mugo… - The Lancet Global …, 2021 - thelancet.com
Background Successful and sustainable models for HIV pre-exposure prophylaxis (PrEP)
delivery in public health systems in Africa are needed. We aimed to evaluate the …