Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development

XL Sun, ZH Chen, X Guo, J Wang, M Ge, SZH Wong… - Developmental Cell, 2023 - cell.com
Cell competition acts as a quality-control mechanism that eliminates cells less fit than their
neighbors to optimize organ development. Whether and how competitive interactions occur …

Longitudinal characteristics of glioblastoma in genome-wide studies

Z Kraboth, B Kalman - Pathology & Oncology Research, 2020 - Springer
Glioblastoma is one of the deadliest tumors with barely over one-year median survival
despite intensive efforts in defining its molecular characteristics and searching for innovative …

Wnt signaling alterations in the human spinal cord of amyotrophic lateral sclerosis cases: spotlight on Fz2 and Wnt5a

C González-Fernández, P Gonzalez… - Molecular …, 2019 - Springer
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with no cure, and
elucidation of the mechanisms mediating neuronal death in this neuropathology is crucial to …

Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma

SK Ray, S Mukherjee - Journal of the Egyptian National Cancer Institute, 2024 - Springer
The progression of metastasis, a complex systemic disease, is facilitated by interactions
between tumor cells and their isolated microenvironments. Over the past few decades …

Dynamics of repurposing synthetic and natural compounds against WNT/β-Catenin signaling in glioma- An in vivo approach

SS Kuduvalli, I Biswas, BK, JM Thomas, A T. S - bioRxiv, 2022 - biorxiv.org
Background Glioblastomas arise from multistep tumorigenesis of the glial cells and are
associated with poor prognosis. Despite the current state-of-art treatment, tumor recurrence …

Tumors of the Nervous System: General Considerations

S Weis, M Sonnberger, A Dunzinger… - Imaging Brain Diseases …, 2019 - Springer
The clinical signs always depend on the location of the tumor and include elevated
intracranial pressure (ICP), focal neurologic deficit, and seizures (focal and/or secondarily …