Huntington's disease (HD) is a progressive, fatal neurodegenerative disease characterized
by motor, cognitive, and psychiatric symptoms. The precise mechanisms of HD progression …

Huntington's disease (HD) is a hereditary neurodegenerative disorder for which there is
currently no effective treatment available. Consequently, the development of appropriate …

Somatic instability of the huntingtin (HTT) CAG repeat mutation modifies age-at-onset of
Huntington's disease (HD). Understanding the mechanism and pathogenic consequences of …

Huntington's disease (HD) is a neurodegenerative disease that causes cognitive,
movement, behavioral, and sleep disturbances, which over time result in progressive …

Sleep deprivation (SD) disrupts circadian rhythms; however, its effects on SD and the
mechanisms involved require further investigation. Previous studies on SD were mainly …

Metabolomics approaches have been used to gain new insights and to identify potential
biomarkers in Huntington's disease (HD) for almost two decades. The present chapter …

Sleep and circadian disruption affects most individuals with Huntington's disease (HD) at
some stage in their lives. Sleep and circadian dysregulation are also present in many mouse …