[HTML][HTML] Recent developments in bioprocessing of recombinant proteins: expression hosts and process development

NK Tripathi, A Shrivastava - Frontiers in Bioengineering and …, 2019 - frontiersin.org
Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

[HTML][HTML] A review of the microbial production of bioactive natural products and biologics

JV Pham, MA Yilma, A Feliz, MT Majid… - Frontiers in …, 2019 - frontiersin.org
A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites,
also known as natural products. Natural products have been a prolific source and an …

New tools for recombinant protein production in Escherichia coli: A 5‐year update

GL Rosano, ES Morales, EA Ceccarelli - Protein science, 2019 - Wiley Online Library
The production of proteins in sufficient amounts is key for their study or use as biotherapeutic
agents. Escherichia coli is the host of choice for recombinant protein production given its fast …

Progress in biopharmaceutical development

M Kesik‐Brodacka - Biotechnology and applied biochemistry, 2018 - Wiley Online Library
Since its introduction in 1982, biopharmaceutical drugs have revolutionized the treatment of
a broad spectrum of diseases and are increasingly used in nearly all branches of medicine …

Chasing bacterial chassis for metabolic engineering: a perspective review from classical to non‐traditional microorganisms

P Calero, PI Nikel - Microbial Biotechnology, 2019 - Wiley Online Library
The last few years have witnessed an unprecedented increase in the number of novel
bacterial species that hold potential to be used for metabolic engineering. Historically …

Nanocarrier vaccines for SARS-CoV-2

J Machhi, F Shahjin, S Das, M Patel… - Advanced Drug Delivery …, 2021 - Elsevier
The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death
associated with substantive social, economic and societal impacts. Treatments rely on re …

[HTML][HTML] Mechanisms of sterile inflammation after intravitreal injection of antiangiogenic drugs: a narrative review

WJ Anderson, NFS da Cruz, LH Lima… - International journal of …, 2021 - Springer
Background Intraocular inflammation is an uncommon but potentially vision-threatening
adverse event related to anti-VEGF therapy. This is of increasing importance given both the …

The microbial ecology of Escherichia coli in the vertebrate gut

E Foster-Nyarko, MJ Pallen - FEMS microbiology reviews, 2022 - academic.oup.com
Escherichia coli has a rich history as biology's 'rock star', driving advances across many
fields. In the wild, E. coli resides innocuously in the gut of humans and animals but is also a …

Fusion tags to enhance heterologous protein expression

MR Ki, SP Pack - Applied Microbiology and Biotechnology, 2020 - Springer
Escherichia coli is the most widely used heterologous protein expression system. However,
this system remains a challenge due to the low solubility of proteins, insufficient yield, and …

[HTML][HTML] Factors involved in heterologous expression of proteins in E. coli host

M Pouresmaeil, S Azizi-Dargahlou - Archives of Microbiology, 2023 - Springer
The production of recombinant proteins is one of the most significant achievements of
biotechnology in the last century. These proteins are produced in the eukaryotic or …