Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …

Background Sharing of equipment used for injecting drug use (IDU) is a substantial cause of
disease burden and a contributor to blood-borne virus transmission. We did a global …

Background Alcohol and drug use can have negative consequences on the health,
economy, productivity, and social aspects of communities. We aimed to use data from the …

Background Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) is
effective in reducing HIV risk in men who have sex with men (MSM). However, concerns …

Executive summary In September, 2015, the member states of the UN endorsed Sustainable
Development Goals (SDGs) for 2030, which aspire to human-rights-centred approaches to …

HIV prevalence is increasing worldwide because people on antiretroviral therapy are living
longer, although new infections decreased from 3· 3 million in 2002, to 2· 3 million in 2012 …

Needle syringe programmes and opioid substitution therapy for preventing hepatitis C
transmission in people who inject drugs - Platt, L - 2017 | Cochrane Library Skip to Content …

Background People who inject drugs (PWID) are a key population affected by the global HIV
and hepatitis C virus (HCV) epidemics. HIV and HCV prevention interventions for PWID …

Background No systematic attempts have been made to estimate the global and regional
prevalence of amphetamine, cannabis, cocaine, and opioid dependence, and quantify their …

Background Social and structural factors are now well accepted as determinants of HIV
vulnerabilities. These factors are representative of social, economic, organizational and …