Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids
A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …
molecule are basically designed to interact with multiple targets or to amplify its effect …
An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill.
Annona cherimola Mill., or the custard apple, is one of the species belonging to the
Annonaceae family, is widely used in traditional medicine, and has been reported to be a …
Annonaceae family, is widely used in traditional medicine, and has been reported to be a …
Proximate composition, phytochemical analysis, and in vitro antioxidant potentials of extracts of Annona muricata (Soursop)
Numerous bioactive compounds and phytochemicals have been reported to be present
Annona muricata (Soursop). Some of these chemical compounds have been linked to the …
Annona muricata (Soursop). Some of these chemical compounds have been linked to the …
[HTML][HTML] In vitro anticancer assessments of Annona muricata fractions and in vitro antioxidant profile of fractions and isolated acetogenin (15-acetyl guanacone)
Annona muricata has been attributed with numerous health benefits–including anticancer
properties. The aim of this study was to carry out anticancer investigations of fractions of …
properties. The aim of this study was to carry out anticancer investigations of fractions of …
Natural insecticides from the Annonaceae: a unique example for developing biopesticides
MB Isman, R Seffrin - Advances in plant biopesticides, 2014 - Springer
The documented negative impacts of synthetic insecticides on the environment as well as on
human health, the consumers' concerns over insecticide residues in foods, and the …
human health, the consumers' concerns over insecticide residues in foods, and the …
Targeted and non-targeted analysis of annonaceous alkaloids and acetogenins from Asimina and Annona species using UHPLC-QToF-MS
In current work, targeted and non-targeted analysis of alkaloids and acetogenins from
methanolic extracts of Asimina, Annona species and dietary supplements have been …
methanolic extracts of Asimina, Annona species and dietary supplements have been …
The Value of Caspase‐3 after the Application of Annona muricata Leaf Extract in COLO‐205 Colorectal Cancer Cell Line
M Abdullah, AF Syam, S Meilany… - Gastroenterology …, 2017 - Wiley Online Library
Annona muricata, commonly known as soursop, contains annonacin, acetogenin, and
polyphenol which are known to have chemopreventive effects on cancer. In this study, we …
polyphenol which are known to have chemopreventive effects on cancer. In this study, we …
Annonaceae acetogenins: A potential treatment for gynecological and breast cancer
DA Bravo-Alfaro, E Montalvo-González… - Fitoterapia, 2024 - Elsevier
Breast and gynecological cancers are major health concerns due to their increasing
incidence rates, and in some cases, their low survival probability. In recent years, multiple …
incidence rates, and in some cases, their low survival probability. In recent years, multiple …
North American pawpaw (Asimina triloba L.) fruit: A critical review of bioactive compounds and their bioactivities.
B Adainoo - Trends in Food Science & Technology, 2024 - Elsevier
Abstract Background The North American pawpaw (Asimina triloba L.) fruit is an
underutilized specialty crop native to North America. Due to the short shelf life of the fruit, it …
underutilized specialty crop native to North America. Due to the short shelf life of the fruit, it …
The effect of an'Annona muricata'leaf extract on nutritional status and cytotoxicity in colorectal cancer: A randomized controlled trial
Background and Objectives: Annona muricata leaf infusion has traditionally been consumed
to maintain health, but is now considered for use in treating cancer patients. The objective of …
to maintain health, but is now considered for use in treating cancer patients. The objective of …