The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Staphylococcus aureus (S. aureus) readily forms biofilms on prosthetic devices such as the
pacemakers, heart valves, orthopaedic implants, and indwelling catheters. Its biofilms are …

Auranofin (AUR) is an orally available lipophilic gold-based anti-inflammatory compound
used for the treatment of rheumatoid arthritis (RA). Recent evidence indicates that AUR may …

Multidrug resistance (MDR) is a significant issue associated with the clinical application of
antibiotics. It is also challenging to discover and develop new antibiotics with novel …

Vaccines have reduced the transmission and severity of COVID‐19, but there remains a
paucity of efficacious treatment for drug‐resistant strains and more susceptible individuals …

Niclosamide (NIC) has demonstrated promising in vitro antiviral efficacy against SARS-CoV-
2, the causative agent of the COVID-19 pandemic. Though NIC is already FDA-approved …

Background Bismuth compounds are known for their activity against multiple
microorganisms; yet, the antibiotic properties of bismuth nanoparticles (BiNPs) remain …

The emergence of new resistance mechanisms, the failure of classical antibiotics in clinic,
the decrease in the development of antibiotics in the industry are all challenges that lead us …

There is a drought of new antibacterial compounds that exploit novel targets. Thioredoxin
reductase (TrxR) from the Gram-positive bacterial antioxidant thioredoxin system has …