Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
Behaviors and disorders related to self-regulation, such as substance use, antisocial
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
The Collaborative Study on the Genetics of Alcoholism: Overview
A Agrawal, SJ Brislin, KK Bucholz… - Genes, Brain and …, 2023 - Wiley Online Library
Alcohol use disorders (AUD) are commonly occurring, heritable and polygenic disorders
with etiological origins in the brain and the environment. To outline the causes and …
with etiological origins in the brain and the environment. To outline the causes and …
The collaborative study on the genetics of alcoholism: Sample and clinical data
The collaborative study on the genetics of alcoholism (COGA) is a multi‐site,
multidisciplinary project with the goal of identifying how genes are involved in alcohol use …
multidisciplinary project with the goal of identifying how genes are involved in alcohol use …
Positive and negative reinforcement are differentially associated with alcohol consumption as a function of alcohol dependence.
A multistage model of drug addiction in which individuals' motivations for use change as
they develop problems is widely accepted; however, the evidence for this model comes …
they develop problems is widely accepted; however, the evidence for this model comes …
Using polygenic scores for identifying individuals at increased risk of substance use disorders in clinical and population samples
Genome-wide, polygenic risk scores (PRS) have emerged as a useful way to characterize
genetic liability. There is growing evidence that PRS may prove useful for early identification …
genetic liability. There is growing evidence that PRS may prove useful for early identification …
COVID-19 pandemic stressors are associated with reported increases in frequency of drunkenness among individuals with a history of alcohol use disorder
JL Meyers, VV McCutcheon… - Translational …, 2023 - nature.com
Some sources report increases in alcohol use have been observed since the start of the
COVID-19 pandemic, particularly among women. Cross-sectional studies suggest that …
COVID-19 pandemic, particularly among women. Cross-sectional studies suggest that …
Genome‐wide association studies of alcohol dependence, DSM‐IV criterion count and individual criteria
Genome‐wide association studies (GWAS) of alcohol dependence (AD) have reliably
identified variation within alcohol metabolizing genes (eg, ADH1B) but have inconsistently …
identified variation within alcohol metabolizing genes (eg, ADH1B) but have inconsistently …
Adolescent depression and substance use: the protective role of prosocial peer behavior
Adolescents with depression disorders have higher rates of substance use. In order to
advance contextually relevant mental health interventions, basic research is needed to test …
advance contextually relevant mental health interventions, basic research is needed to test …
Genetic nurture effects for alcohol use disorder
We tested whether aspects of the childhood/adolescent home environment mediate genetic
risk for alcohol problems within families across generations. Parental relationship discord …
risk for alcohol problems within families across generations. Parental relationship discord …
Cannabis recreational legalization and prevalence of simultaneous cannabis and alcohol use in the United States
PD Gonçalves, NS Levy, LE Segura… - Journal of general …, 2023 - Springer
Background Simultaneous cannabis/alcohol use, using both substances within a short time
interval so that their effects overlap, has a greater risk of potential negative consequences …
interval so that their effects overlap, has a greater risk of potential negative consequences …