[HTML][HTML] Synthesis and analgesic activity of novel hydrazide and hydrazine derivatives

MN Koopaei, MJ Assarzadeh, A Almasirad… - Iranian Journal of …, 2013 - ncbi.nlm.nih.gov
The uses of non-steroidal anti-inflammatory drugs (NSAIDs) are limited by a variety of side
effects. So research on preparing new analgesic agents is important. According to some …

Indole‐3‐carbaldehyde Semicarbazone Derivatives: Synthesis, Characterization, and Antibacterial Activities

F Carrasco, W Hernández, O Chupayo… - Journal of …, 2020 - Wiley Online Library
Four indole‐3‐carbaldehyde semicarbazone derivatives, 2‐((5‐bromo‐1H‐indol‐3‐yl)
methylene) hydrazinecarboxamide (1), 2‐((5‐chloro‐1H‐indol‐3‐yl) methylene) …

Semicarbazone analogs as anticonvulsant agents: a review

M Jawed Ahsan - Central Nervous System Agents in Medicinal …, 2013 - ingentaconnect.com
Semicarbazones are synthesized by the condensation of semicarbazide and
aldehyde/ketone. The literature survey revealed that semicarbazones had been emerged as …

Synthesis and analgesic activity of new 1, 3, 4-oxadiazoles and 1, 2, 4-triazoles

A Almasirad, A Shafiee, M Abdollahi… - Medicinal Chemistry …, 2011 - Springer
Abstract A series of new 1, 3, 4-oxadiazoles and 1, 2, 4-triazoles were synthesized in order
to obtain new compounds with potential analgesic activity. Compounds were evaluated for …

[HTML][HTML] Synthesis of two novel 3-amino-5-[4-chloro-2-phenoxyphenyl]-4H-1, 2, 4-triazoles with anticonvulsant activity

M Mahdavi, T Akbarzadeh, V Sheibani… - Iranian Journal of …, 2010 - ncbi.nlm.nih.gov
Abstract Two novel 3-amino-5-(4-choloro-2-phenoxyphenyl)-4H-1, 2, 4-triazole derivatives
were prepared and their anticonvulsant activity was measured by evaluation of the ability of …

New trifluoromethyl-containing (E)-N′-arylidene-[3-alkyl (aryl/heteroaryl)-4, 5-dihydro-1H-pyrazol-1-yl] carbohydrazides: Synthesis, crystal structure and antimicrobial …

HG Bonacorso, S Cavinatto, PT Campos… - Journal of Fluorine …, 2012 - Elsevier
A new series of twenty-one trifluoromethyl-containing (E)-N′-arylidene-1H-pyrazole-1-
carbohydrazides (4) was synthesized by the cyclocondensation reactions of six 3-alkyl …

Augmentation of GABAergic neurotransmission by novel N-(substituted)-2-[4-(substituted) benzylidene] hydrazinecarbothioamides—a potential anticonvulsant …

L Tripathi, P Kumar - European journal of medicinal chemistry, 2013 - Elsevier
New N-(substituted)-2-[4-(substituted) benzylidene] hydrazinecarbothioamides were
designed, synthesized and evaluated for anticonvulsant activity and neurotoxicity. The …

Synthesis and evaluation of some novel methylene-bridged aryl semicarbazones as potential anticonvulsant agents

S Mozaffari, S Ghasemi, H Baher, H Khademi… - Medicinal chemistry …, 2012 - Springer
A series of aryl semicarbazones containing a methylene bridge in their skeleton were
synthesized as anticonvulsant agents. The strategy of introducing a methylene bridge was to …

Synthesis and in silico ADMET evaluation of new thiazole and thiazolidine-4-one derivatives as non-ulcerogenic analgesic and anti-inflammatory agents

KM Nassiri, M Monavari, N Vousooghi… - Journal of the Serbian …, 2024 - doiserbia.nb.rs
A series of 1, 3-thiazoline-4-one derivatives bearing 2-phenoxyphenyl moiety, were
synthesized as potential new analgesic and anti-inflammatory agents. The structures were …

Synthesis and antiseizure activity of (E)-1,2-diarylethylidenehydrazine carboximidamides against tonic-clonic seizures: an intracerebroventricular and …

FA Firouzjaei, E Heidarli, S Ravan, SM Hosseini… - Medicinal Chemistry …, 2020 - Springer
Abstract A series of (E)-1, 2-diarylethylidenehydrazine carboximidamides 2a–j were
synthesized and characterized by NOESY experiment as anticonvulsant agents and their …