Programmed cell death is a basic cellular mechanism. Apoptotic-like programmed cell death
(called apoptosis in animals) occurs in both unicellular and multicellular eukaryotes, and …

Organismal development and function requires multiple and accurate signal transduction
pathways to ensure that proper balance between cell proliferation, differentiation …

Acute ischemic stroke is a critical condition that can result in disability and death. The
consequences of this medical condition depend on various factors, including the size of the …

The phenotypic and biochemical similarities between caspase-mediated apoptosis and
cellular differentiation are striking. They include such diverse phenomenon as mitochondrial …

Muscle atrophy derived from excessive proteolysis is a hallmark of numerous disease
conditions. Accordingly, the negative consequences of skeletal muscle protein breakdown …

It has become clear that mitochondrial reactive oxygen species (mtROS) are not simply
villains and mitochondria the hapless targets of their attacks. Rather, it appears that …

Compensatory growth and regeneration of skeletal muscle is dependent on the resident
stem cell population, satellite cells (SCs). Self-renewal and maintenance of the SC niche is …

Current evidence has associated caspase activation with the regulation of basic cellular
functions without causing apoptosis. Malfunction of non‐apoptotic caspase activities may …

Muscle homeostasis is guaranteed by a delicate balance between synthesis and
degradation of cell proteins and its alteration leads to muscle wasting and diseases. In this …

The post-natal heart adapts to stress and overload through hypertrophic growth, a process
that may be pathologic or beneficial (physiologic hypertrophy). Physiologic hypertrophy …