Ferroptosis is a type of lipid peroxidation-dependent cell death that is emerging as a
therapeutic target for cancer. However, the mechanisms of ferroptosis during the generation …

Studies over the past three years have substantially expanded the involvements of
eukaryotic initiation factor 3 (eIF3) in messenger RNA (mRNA) translation. It now appears …

Coronavirus disease 2019 or COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has become a significant threat to the health of human beings …

HuR (human antigen R), an mRNA-binding protein responsible for poor prognosis in nearly
all kinds of malignancies, is a potential anti-tumor target for drug development. While …

In this 2nd edition of “Neuroendocrine Research in Health and Disease”, we collected
papers of neuroendocrine research in the following themes. 1. Mental health and …

Hematophagous insects transmit infectious diseases. Sand flies are vectors of
leishmaniasis, but can also transmit viruses. We have been studying immune responses of …

Eltrombopag is a small molecule TPO-R agonist that has been shown in our previous
studies to inhibit tumor growth by targeting Human antigen R (HuR) protein. HuR protein not …

Background Metastatic of breast cancer is one of the leading causes of cancer-related
death. HuR is an mRNA binding protein, which could regulate mRNA stability of multiple …

Internal ribosomal entry site (IRES) functions as a cis-acting RNA element, which drives an
alternative and cap-independent translation initiation pathway. Currently, there are few …

Internal ribosome entry sites (IRES) are segments of the mRNA found in untranslated
regions, which can recruit the ribosome and initiate translation independently of the more …