Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective

S Bindu, S Mazumder, U Bandyopadhyay - Biochemical pharmacology, 2020 - Elsevier
Owing to the efficacy in reducing pain and inflammation, non-steroidal anti-inflammatory
drugs (NSAIDs) are amongst the most popularly used medicines confirming their position in …

Adverse effects of nonsteroidal antiinflammatory drugs: an update of gastrointestinal, cardiovascular and renal complications

S Harirforoosh, W Asghar… - Journal of Pharmacy & …, 2013 - journals.library.ualberta.ca
Non-steroidal anti-inflammatory drugs (NSAIDs) are used chronically to reduce pain and
inflammation in patients with arthritic conditions, and also acutely as analgesics by many …

The read-across hypothesis and environmental risk assessment of pharmaceuticals

M Rand-Weaver, L Margiotta-Casaluci… - … science & technology, 2013 - ACS Publications
Pharmaceuticals in the environment have received increased attention over the past
decade, as they are ubiquitous in rivers and waterways. Concentrations are in sub-ng to low …

Efficacy and safety of NSAIDs in infants: a comprehensive review of the literature of the past 20 years

VC Ziesenitz, T Welzel, M van Dyk, P Saur, M Gorenflo… - Pediatric Drugs, 2022 - Springer
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in infants, children, and
adolescents worldwide; however, despite sufficient evidence of the beneficial effects of …

The effect of pharmacogenetic profiling with a clinical decision support tool on healthcare resource utilization and estimated costs in the elderly exposed to …

D Brixner, E Biltaji, A Bress, S Unni, X Ye… - Journal of medical …, 2016 - Taylor & Francis
Objective: To compare healthcare resource utilization (HRU) and clinical decision-making
for elderly patients based on cytochrome P450 (CYP) pharmacogenetic testing and the use …

Clinical Efficacy, Pharmacokinetics, and Safety of the Available Medical Options in the Treatment of Endometriosis-Related Pelvic Pain: A Scoping Review

M Mikuš, M Šprem Goldštajn, AS Laganà, F Vukorepa… - Pharmaceuticals, 2023 - mdpi.com
Background: In this scoping review, we sought to identify published studies evaluating the
drugs currently used in the treatment of endometriosis-related pelvic pain, with reflection on …

Drug–drug interactions in vestibular diseases, clinical problems, and medico-legal implications

G Di Mizio, G Marcianò, C Palleria, L Muraca… - International Journal of …, 2021 - mdpi.com
Peripheral vestibular disease can be treated with several approaches (eg, maneuvers,
surgery, or medical approach). Comorbidity is common in elderly patients, so polytherapy is …

Variability in analgesic response to non-steroidal anti-inflammatory drugs

KN Theken - Prostaglandins & other lipid mediators, 2018 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used agents
for the treatment of acute and chronic pain. However, it has long been recognized that there …

[PDF][PDF] Anti-inflammatory and antioxidant effect of Ceratonia siliqua L. methanol barks extract

N Lachkar, M Al-Sobarry, H El Hajaji… - J Chem Pharm …, 2016 - researchgate.net
Ceratonia siliqua L. has been used in Moroccan traditional medicine as antidiarrheal and
diuretic. The infusion of carob leaves is used as an emetic for acute poisoning. The present …

Celecoxib is a substrate of CYP2D6: Impact on celecoxib metabolism in individuals with CYP2C9* 3 variants

YA Siu, MH Hao, V Dixit, WG Lai - Drug metabolism and pharmacokinetics, 2018 - Elsevier
Celecoxib was characterized as a substrate of human cytochrome P450 (CYP) 2D6 in vitro.
In recombinant CYP2D6, celecoxib hydroxylation showed atypical substrate inhibition …