Cells continuously produce free radicals and reactive oxygen species (ROS) as part of
metabolic processes. These free radicals are neutralized by an elaborate antioxidant …

The topic of exercise-induced oxidative stress has received considerable attention in recent
years, with close to 300 original investigations published since the early work of Dillard and …

Although assays for the most popular markers of exercise-induced oxidative stress may
experience methodological flaws, there is sufficient credible evidence to suggest that …

Increased oxidative stress, defined as an imbalance between prooxidants and antioxidants,
resulting in molecular damage and disruption of redox signaling, is associated with …

In recent years, the altitude acclimatization responses elicited by short-term intermittent
exposure to hypoxia have been subject to renewed attention. The main goal of short-term …

A significant portion of the world's geography lies above 10,000 feet elevation, an arbitrary
designation that separates moderate and high altitude. Although the number of indigenous …

It is well-established that different altitude training modalities can improve convective oxygen
(O2) transport capacity and physical fitness of athletes (Millet et al., 2010). Exercising in …

Acute mountain sickness (AMS) is a neurological disorder that typically affects mountaineers
who ascend to high altitude. The symptoms have traditionally been ascribed to intracranial …

This study investigates whether a 6-wk intermittent hypoxia training (IHT), designed to avoid
reductions in training loads and intensities, improves the endurance performance capacity of …

The oxidation of lipids yields both primary and secondary oxidation compounds that produce
undesirable biological effects [1–3] and includes loss of nutritional value and sensory …