[HTML][HTML] Fluoroquinolones hybrid molecules as promising antibacterial agents in the fight against antibacterial resistance

IA Lungu, OL Moldovan, V Biriș, A Rusu - Pharmaceutics, 2022 - mdpi.com
The emergence of bacterial resistance has motivated researchers to discover new
antibacterial agents. Nowadays, fluoroquinolones keep their status as one of the essential …

[HTML][HTML] MRGPRX2 and adverse drug reactions

BD McNeil - Frontiers in immunology, 2021 - frontiersin.org
Many adverse reactions to therapeutic drugs appear to be allergic in nature, and are thought
to be triggered by patient-specific Immunoglobulin E (IgE) antibodies that recognize the drug …

Importance of relating efficacy measures to unbound drug concentrations for anti-infective agents

D Gonzalez, S Schmidt… - Clinical microbiology …, 2013 - Am Soc Microbiol
For the optimization of dosing regimens of anti-infective agents, it is imperative to have a
good understanding of pharmacokinetics (PK) and pharmacodynamics (PD). Whenever …

Antimicrobial therapy for chronic bacterial prostatitis

G Perletti, E Marras… - Cochrane Database …, 2013 - cochranelibrary.com
Background Chronic bacterial prostatitis (CBP) is frequently diagnosed in men of fertile age,
and is characterized by a disabling array of symptoms, including pain in the pelvic area (for …

Bacterial prostatitis

FME Wagenlehner, A Pilatz, T Bschleipfer… - World journal of …, 2013 - Springer
Objectives The prostatitis syndrome is classified into bacterial prostatitis (acute and chronic),
chronic pelvic pain syndrome and asymptomatic prostatitis. The aim of this report is to review …

[HTML][HTML] Fluoroquinolone–macrolide combination therapy for chronic bacterial prostatitis: retrospective analysis of pathogen eradication rates, inflammatory findings …

V Magri, E Montanari, V Škerk, A Markotić… - Asian journal of …, 2011 - ncbi.nlm.nih.gov
We previously demonstrated the safety and efficacy of fluoroquinolone–macrolide
combination therapy in category II chronic bacterial prostatitis (CBP). The aim of this study is …

[HTML][HTML] Молекулярные и метаболические аспекты мужского бесплодия

ВН Павлов, ЭФ Галимова, БФ Терегулов… - Вестник …, 2016 - cyberleninka.ru
В обзоре на основе собственных и литературных данных рассмотрены молекулярные
и метаболические предпосылки развития идиопатического бесплодия у мужчин …

Insight view on possible role of fluoroquinolones in cancer therapy

PC Sharma, M Chaudhary, A Sharma… - Current topics in …, 2013 - ingentaconnect.com
Cancer is a disease without limits turning out to be prime cause for raising death toll around
the world. Several treatment strategies including chemotherapy, surgery and radiotherapy …

Population pharmacokinetic modeling of the unbound levofloxacin concentrations in rat plasma and prostate tissue measured by microdialysis

FK Hurtado, B Weber, H Derendorf… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Levofloxacin is a broad-spectrum fluoroquinolone used in the treatment of both acute and
chronic bacterial prostatitis. Currently, the treatment of bacterial prostatitis is still difficult …

Macrolides for the treatment of chronic bacterial prostatitis: an effective application of their unique pharmacokinetic and pharmacodynamic profile

G Perletti, V Skerk, V Magri… - Molecular …, 2011 - spandidos-publications.com
Chronic bacterial prostatitis (CBP) is a persistent infection of the prostate characterized by
poor quality of life mainly due to frequent relapse episodes caused by incomplete …