Antimicrobial peptides as anticancer agents: functional properties and biological activities
Antimicrobial peptides (AMPs), or host defense peptides, are small cationic or amphipathic
molecules produced by prokaryotic and eukaryotic organisms that play a key role in the …
molecules produced by prokaryotic and eukaryotic organisms that play a key role in the …
Antimicrobial peptides: mechanism of action, activity and clinical potential
QY Zhang, ZB Yan, YM Meng, XY Hong, G Shao… - Military Medical …, 2021 - Springer
The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …
Human antimicrobial peptides and proteins
G Wang - Pharmaceuticals, 2014 - mdpi.com
As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …
Cathelicidins modulate TLR-activation and inflammation
MR Scheenstra, RM Van Harten… - Frontiers in …, 2020 - frontiersin.org
Cathelicidins are short cationic peptides that are part of the innate immune system. At first,
these peptides were studied mostly for their direct antimicrobial killing capacity, but …
these peptides were studied mostly for their direct antimicrobial killing capacity, but …
Design of antimicrobial peptides: progress made with human cathelicidin LL-37
The incorporation of the innate immune system into humans is essential for survival and
health due to the rapid replication of invading microbes and the delayed action of the …
health due to the rapid replication of invading microbes and the delayed action of the …
Clinical applications of antimicrobial peptides (AMPs): where do we stand now?
In this era of multi-drug resistance (MDR), antimicrobial peptides (AMPs) are one of the most
promising classes of potential drug candidates to combat communicable as well as …
promising classes of potential drug candidates to combat communicable as well as …
The human cathelicidin antimicrobial peptide LL-37 and mimics are potential anticancer drugs
K Kuroda, K Okumura, H Isogai, E Isogai - Frontiers in oncology, 2015 - frontiersin.org
Antimicrobial peptides (AMPs) play a critical role in innate host defense against microbial
pathogens in many organisms. The human cathelicidin, LL-37, has a net positive charge …
pathogens in many organisms. The human cathelicidin, LL-37, has a net positive charge …
Glioblastoma hijacks microglial gene expression to support tumor growth
Background Glioblastomas are the most common and lethal primary brain tumors. Microglia,
the resident immune cells of the brain, survey their environment and respond to pathogens …
the resident immune cells of the brain, survey their environment and respond to pathogens …
LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity
A Fabisiak, N Murawska, J Fichna - Pharmacological Reports, 2016 - Elsevier
Antimicrobial peptides (AMPs) is a large family of compounds serving as natural antibiotics,
widely distributed across the organism, mainly in mucus layers. They are designed to …
widely distributed across the organism, mainly in mucus layers. They are designed to …
Regulation of inflammation by members of the formyl-peptide receptor family
K Chen, Z Bao, W Gong, P Tang, T Yoshimura… - Journal of …, 2017 - Elsevier
Inflammation is associated with a variety of diseases. The hallmark of inflammation is
leukocyte infiltration at disease sites in response to pathogen-or damage-associated …
leukocyte infiltration at disease sites in response to pathogen-or damage-associated …