Hydrogels are crosslinked polymer chains with three-dimensional (3D) network structures,
which can absorb relatively large amounts of fluid. Because of the high water content, soft …

Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …

One of the major impediments to drug development is low aqueous solubility and thus poor
bioavailability, which leads to insufficient clinical utility. Around 70–80% of drugs in the …

Cocrystals are an emerging class of crystalline materials composed of two or more different
molecules in the same crystal lattice that are physically connected by non-ionic and non …

Herein, thermosensitive blends of poloxamer 407 (P407)/poloxamer 188
(P188)/polycarbophil (PCB) were developed in terms of maximized content of PCB (a …

There is a dearth of natural remedies available for the treatment of an increasing number of
diseases facing mankind. Natural products may provide an opportunity to produce …

Numerous studies in the literature have proposed the use of thermo-responsive hydrogels
for filling cavities after tumor resection. However, optimizing the injection process is …

The aqueous solution of binary mixtures of amphiphilic copolymers is a potential platform for
fabricating mixed polymeric micelles for pharmaceutical applications, particularly in …

Recently, non-covalent reactions have emerged as approaches to improve the
physicochemical properties of active pharmaceutical ingredients (API), including antibiotics …

A novel polyimide-bridge covalent organic framework-based (PI-COF) hybrid was
synthesized through simple green chemistry between PI-COF and MCM-NH2 monomers as …