Genetic control of biosynthesis and transport of riboflavin and flavin nucleotides and construction of robust biotechnological producers
CA Abbas, AA Sibirny - Microbiology and molecular biology …, 2011 - Am Soc Microbiol
SUMMARY Riboflavin [7, 8-dimethyl-10-(1′-d-ribityl) isoalloxazine, vitamin B2] is an
obligatory component of human and animal diets, as it serves as the precursor of flavin …
obligatory component of human and animal diets, as it serves as the precursor of flavin …
One hundred years of vitamins—A success story of the natural sciences
M Eggersdorfer, D Laudert, U Letinois… - Angewandte Chemie …, 2012 - Wiley Online Library
The discovery of vitamins as essential factors in the diet was a scientific breakthrough that
changed the world. Diseases such as scurvy, rickets, beriberi, and pellagra were recognized …
changed the world. Diseases such as scurvy, rickets, beriberi, and pellagra were recognized …
Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast
R Chen, J Gao, W Yu, X Chen, X Zhai, Y Chen… - Nature Chemical …, 2022 - nature.com
Advances in synthetic biology enable microbial hosts to synthesize valuable natural
products in an efficient, cost-competitive and safe manner. However, current engineering …
products in an efficient, cost-competitive and safe manner. However, current engineering …
[HTML][HTML] A new measure for functional similarity of gene products based on Gene Ontology
Abstract Background Gene Ontology (GO) is a standard vocabulary of functional terms and
allows for coherent annotation of gene products. These annotations provide a basis for new …
allows for coherent annotation of gene products. These annotations provide a basis for new …
[HTML][HTML] Microbial cell factories for the sustainable manufacturing of B vitamins
CG Acevedo-Rocha, LS Gronenberg, M Mack… - Current opinion in …, 2019 - Elsevier
Highlights•Industrially produced B vitamins are widely used in feed, food, cosmetics and
pharma.•Most B vitamins are produced by chemical synthesis in a non-sustainable …
pharma.•Most B vitamins are produced by chemical synthesis in a non-sustainable …
[HTML][HTML] Riboflavin as a promising antimicrobial agent? A multi-perspective review
Riboflavin, or more commonly known as vitamin B2, forms part of the component of vitamin B
complex. Riboflavin consisting of two important cofactors, flavin mononucleotide (FMN) and …
complex. Riboflavin consisting of two important cofactors, flavin mononucleotide (FMN) and …
Biotechnology of riboflavin
SK Schwechheimer, EY Park, JL Revuelta… - Applied microbiology …, 2016 - Springer
Riboflavin (vitamin B 2) production has shifted from chemical synthesis to exclusive
biotechnological synthesis in less than 15 years. The underlying extraordinary achievement …
biotechnological synthesis in less than 15 years. The underlying extraordinary achievement …
Lactic acid bacteria as a cell factory for riboflavin production
Consumers are increasingly becoming aware of their health and nutritional requirements,
and in this context, vitamins produced in situ by microbes may suit their needs and …
and in this context, vitamins produced in situ by microbes may suit their needs and …
[HTML][HTML] Microbial cell factories for green production of vitamins
Y Wang, L Liu, Z Jin, D Zhang - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Vitamins are a group of essential nutrients that are necessary to maintain normal metabolic
activities and optimal health. There are wide applications of different vitamins in food …
activities and optimal health. There are wide applications of different vitamins in food …
Coenzymes and their role in the evolution of life
A Kirschning - Angewandte Chemie International Edition, 2021 - Wiley Online Library
The evolution of coenzymes, or their impact on the origin of life, is fundamental for
understanding our own existence. Having established reasonable hypotheses about the …
understanding our own existence. Having established reasonable hypotheses about the …