Robust tools for analysing gene function in Plasmodium parasites, which are the causative
agents of malaria, are being developed at an accelerating rate. Two decades after genetic …

Research into the complex genetic underpinnings of the malaria parasite Plasmodium
falciparum is entering a new era with the arrival of site-specific genome engineering …

Research into the aetiological agent of the most widespread form of severe malaria,
Plasmodium falciparum, has benefitted enormously from the ability to culture and genetically …

The origin of all mitochondria can be traced to the symbiotic arrangement that resulted in the
emergence of eukaryotes in a world that was exclusively populated by prokaryotes,,. This …

The apicoplast and mitochondrion of the malaria parasite Plasmodium falciparum are
important intracellular organelles and targets of several anti-malarial drugs. In recent years …

The malaria parasite Plasmodium falciparum undergoes antigenic variation to evade host
immune responses through switching expression of variant surface proteins encoded by the …

Despite over a century of study of malaria parasites, parts of the Plasmodium falciparum life
cycle remain virtually unknown. One of these is the early gametocyte stage, a round shaped …

Plasmodium parasites are unicellular eukaryotes that undergo a series of remarkable
morphological transformations during the course of a multistage life cycle spanning two …

Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and
peripheral microvasculature is linked to morbidity and mortality associated with severe …

Mono-allelic expression of gene families is used by many organisms to mediate phenotypic
variation of surface proteins. In the apicomplexan parasite Plasmodium falciparum …