Alterations in cardiac energy metabolism contribute to the severity of heart failure. However,
the energy metabolic changes that occur in heart failure are complex and are dependent not …

Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth.
Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual …

Diabetes is a chronic metabolic disease that is increasing in prevalence and causes many
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …

Diabetes causes cardiomyopathy and increases the risk of heart failure independent of
hypertension and coronary heart disease. This condition called “Diabetic Cardiomyopathy” …

Diabetes mellitus-related cardiomyopathy (DMCMP) was originally described as a dilated
phenotype with eccentric left ventricular (LV) remodelling and systolic LV dysfunction …

The prevalence of obesity, insulin resistance and diabetes is increasing rapidly. Most
patients with these disorders have hypertriglyceridaemia and increased plasma levels of …

The network for cardiac fuel metabolism contains intricate sets of interacting pathways that
result in both ATP-producing and non–ATP-producing end points for each class of energy …

Exercise plays a central role in the management and treatment of common metabolic
diseases, but modern society presents many barriers to exercise. Over the past decade …

Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

Heart disease is a leading cause of death worldwide. In many forms of heart disease,
including heart failure, ischaemic heart disease and diabetic cardiomyopathies, changes in …