Roles and inhibitors of FAK in cancer: current advances and future directions

HH Hu, SQ Wang, HL Shang, HF Lv… - Frontiers in …, 2024 - frontiersin.org
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that exhibits high expression
in various tumors and is associated with a poor prognosis. FAK activation promotes tumor …

Unraveling the multifaceted role of EpCAM in colorectal cancer: an integrated review of its function and interplay with non-coding RNAs

X Jiang, S Wang, Q Liang, Y Liu, L Liu - Medical Oncology, 2023 - Springer
The epithelial cell adhesion molecule (EpCAM) is a critical glycoprotein involved in cell
cycle progression, proliferation, differentiation, migration, and immune evasion. Its role as a …

Intracellular domain of epithelial cell adhesion molecule induces Wnt receptor transcription to promote colorectal cancer progression

SS Panda, CC Lee, K Geevimaan, KC Chen… - Journal of Biomedical …, 2024 - Springer
Background Epithelial cell adhesion molecule (EpCAM) has been widely studied as a tumor
antigen due to its expression in varieties of solid tumors. Moreover, the glycoprotein …

Correction: Epithelial cell adhesion molecule (EpCAM) regulates HGFR signaling to promote colon cancer progression and metastasis

CC Lee, CJ Yu, SS Panda, KC Chen, KH Liang… - Journal of Translational …, 2024 - Springer
Following publication of the original article [1], we have been notified about the errors in Fig.
7A, B, G. In Fig. 7A, B, the label of NMIgG should be revise to “–” in the EpAb2-6 and …

Single‐cell transcriptomics reveal metastatic CLDN4+ cancer cells underlying the recurrence of malignant pleural effusion in patients with advanced non‐small‐cell …

X Zhang, X Wang, Y Wen, S Chen… - Clinical and …, 2024 - Wiley Online Library
Background Recurrent malignant pleural effusion (MPE) resulting from non‐small‐cell lung
cancer (NSCLC) is easily refractory to conventional therapeutics and lacks predictive …

Informed by Cancer Stem Cells of Solid Tumors: Advances in Treatments Targeting Tumor-Promoting Factors and Pathways

MR MacLean, OL Walker, RP Arun… - International Journal of …, 2024 - mdpi.com
Cancer stem cells (CSCs) represent a subpopulation within tumors that promote cancer
progression, metastasis, and recurrence due to their self-renewal capacity and resistance to …

The Predictive Value of Neutrophil Extracellular Trap-Related Risk Score in Prognosis and Immune Microenvironment of Colorectal Cancer Patients

J Dong, J Zhao, Z Wu, J Liu, B Wang, X Qi - Molecular Biotechnology, 2024 - Springer
Colorectal cancer (CRC) has brought great healthy burden for patients. Neutrophil
extracellular traps (NETs) have been explored in several tumors, while it remains largely …

[HTML][HTML] МИРОВЫЕ ИССЛЕДОВАНИЯ ФИЗИОЛОГИЧЕСКИХ ОСОБЕННОСТЕЙ НЕКОТОРЫХ CD МАРКЕРОВ, СВЯЗАННЫХ СО СТВОЛОВЫМИ КЛЕТКАМИ В …

ДЗ Иргашева, АС Муртазо, ФА Шукуров… - Биология и …, 2023 - cyberleninka.ru
Мезенхимальные стволовые клетки, происходящие из различных тканей взрослого
организма, прикрепляются к чашкам для культивирования тканей и экспрессируют …