Epigenetics and DOHaD: from basics to birth and beyond

T Bianco-Miotto, JM Craig, YP Gasser… - … origins of health and …, 2017 - cambridge.org
Developmental origins of health and disease (DOHaD) is the study of how the early life
environment can impact the risk of chronic diseases from childhood to adulthood and the …

Epigenetics and the environment: emerging patterns and implications

R Feil, MF Fraga - Nature reviews genetics, 2012 - nature.com
Epigenetic phenomena in animals and plants are mediated by DNA methylation and stable
chromatin modifications. There has been considerable interest in whether environmental …

Beyond DNA: integrating inclusive inheritance into an extended theory of evolution

É Danchin, A Charmantier, FA Champagne… - Nature reviews …, 2011 - nature.com
Many biologists are calling for an'extended evolutionary synthesis' that would'modernize the
modern synthesis' of evolution. Biological information is typically considered as being …

Food as exposure: Nutritional epigenetics and the new metabolism

H Landecker - BioSocieties, 2011 - Springer
Nutritional epigenetics seeks to explain the effects of nutrition on gene expression. For
social science, it is an area of life science whose analysis reveals a concentrated form of a …

DNA methylation as a future therapeutic and diagnostic target in rheumatoid arthritis

M Ciechomska, L Roszkowski, W Maslinski - Cells, 2019 - mdpi.com
Rheumatoid arthritis (RA) is a long-term autoimmune disease of unknown etiology that leads
to progressive joint destruction and ultimately to disability. RA affects as much as 1% of the …

Epigenetic perspective on the developmental effects of bisphenol A

M Kundakovic, FA Champagne - Brain, behavior, and immunity, 2011 - Elsevier
Bisphenol A (BPA) is an estrogenic environmental toxin widely used in the production of
plastics and ubiquitous human exposure to this chemical has been proposed to be a …

Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis

WP Arend, GS Firestein - Nature Reviews Rheumatology, 2012 - nature.com
Multiple proven and potential risk factors for the development of rheumatoid arthritis (RA)
have been identified, and represent interactions between genes and the environment …

Zebrafish (Danio rerio) as an excellent vertebrate model for the development, reproductive, cardiovascular, and neural and ocular development toxicity study of …

C Shen, Z Zuo - Environmental Science and Pollution Research, 2020 - Springer
In the past decades, the type of chemicals has gradually increased all over the world, and
many of these chemicals may have a potentially toxic effect on human health. The zebrafish …

Epigenetics and its implications for ecotoxicology

MB Vandegehuchte, CR Janssen - Ecotoxicology, 2011 - Springer
Epigenetics is the study of mitotically or meiotically heritable changes in gene function that
occur without a change in the DNA sequence. Interestingly, epigenetic changes can be …

Epigenetic inheritance of disease and disease risk

J Bohacek, IM Mansuy - Neuropsychopharmacology, 2013 - nature.com
Epigenetic marks in an organism can be altered by environmental factors throughout life.
Although changes in the epigenetic code can be positive, some are associated with severe …