Leukocidins: staphylococcal bi-component pore-forming toxins find their receptors

AN Spaan, JAG van Strijp, VJ Torres - Nature Reviews Microbiology, 2017 - nature.com
Staphylococcus aureus is a major bacterial pathogen that causes disease worldwide. The
emergence of strains that are resistant to commonly used antibiotics and the failure of …

Waves of resistance: Staphylococcus aureus in the antibiotic era

HF Chambers, FR DeLeo - Nature reviews microbiology, 2009 - nature.com
Staphylococcus aureus is notorious for its ability to become resistant to antibiotics. Infections
that are caused by antibiotic-resistant strains often occur in epidemic waves that are initiated …

Intracellular Staphylococcus aureus persisters upon antibiotic exposure

F Peyrusson, H Varet, TK Nguyen, R Legendre… - Nature …, 2020 - nature.com
Bacterial persister cells are phenotypic variants that exhibit a transient non-growing state
and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus …

A genetic resource for rapid and comprehensive phenotype screening of nonessential Staphylococcus aureus genes

PD Fey, JL Endres, VK Yajjala, TJ Widhelm, RJ Boissy… - MBio, 2013 - Am Soc Microbiol
To enhance the research capabilities of investigators interested in Staphylococcus aureus,
the Nebraska Center for Staphylococcal Research (CSR) has generated a sequence …

AI-2-mediated signalling in bacteria

CS Pereira, JA Thompson… - FEMS microbiology …, 2013 - academic.oup.com
Success in nature depends upon an ability to perceive and adapt to the surrounding
environment. Bacteria are not an exception; they recognize and constantly adjust to …

Community-associated meticillin-resistant Staphylococcus aureus

FR DeLeo, M Otto, BN Kreiswirth, HF Chambers - The Lancet, 2010 - thelancet.com
Meticillin-resistant Staphylococcus aureus (MRSA) is endemic in hospitals worldwide, and
causes substantial morbidity and mortality. Health-care-associated MRSA infections arise in …

Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo

LR Thurlow, ML Hanke, T Fritz, A Angle… - The Journal of …, 2011 - journals.aai.org
Biofilms are complex communities of bacteria encased in a matrix composed primarily of
polysaccharides, extracellular DNA, and protein. Staphylococcus aureus can form biofilm …

Transforming the untransformable: application of direct transformation to manipulate genetically Staphylococcus aureus and Staphylococcus epidermidis

IR Monk, IM Shah, M Xu, MW Tan, TJ Foster - MBio, 2012 - Am Soc Microbiol
The strong restriction barrier present in Staphylococcus aureus and Staphylococcus
epidermidis has limited functional genomic analysis to a small subset of strains that are …

Interactions of Methicillin Resistant Staphylococcus aureus USA300 and Pseudomonas aeruginosa in Polymicrobial Wound Infection

I Pastar, AG Nusbaum, J Gil, SB Patel, J Chen… - PloS one, 2013 - journals.plos.org
Understanding the pathology resulting from Staphylococcus aureus and Pseudomonas
aeruginosa polymicrobial wound infections is of great importance due to their ubiquitous …

Phenol-soluble modulins–critical determinants of staphylococcal virulence

GYC Cheung, HS Joo, SS Chatterjee… - FEMS microbiology …, 2014 - academic.oup.com
Phenol-soluble modulins (PSMs) are a recently discovered family of amphipathic, alpha-
helical peptides that have multiple roles in staphylococcal pathogenesis and contribute to a …