Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
[HTML][HTML] Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person
L Koklesova, A Mazurakova, M Samec, K Biringer… - EPMA Journal, 2021 - Springer
Homocysteine (Hcy) metabolism is crucial for regulating methionine availability, protein
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …
homeostasis, and DNA-methylation presenting, therefore, key pathways in post-genomic …
Exercise-linked skeletal irisin ameliorates diabetes-associated osteoporosis by inhibiting the oxidative damage–dependent miR-150-FNDC5/pyroptosis axis
Recent evidence suggests that physical exercise (EX) promotes skeletal development.
However, the impact of EX on the progression of bone loss and deterioration of mechanical …
However, the impact of EX on the progression of bone loss and deterioration of mechanical …
[HTML][HTML] Dysregulation of epigenetic mechanisms of gene expression in the pathologies of hyperhomocysteinemia
J Perła-Kaján, H Jakubowski - International journal of molecular sciences, 2019 - mdpi.com
Hyperhomocysteinemia (HHcy) exerts a wide range of biological effects and is associated
with a number of diseases, including cardiovascular disease, dementia, neural tube defects …
with a number of diseases, including cardiovascular disease, dementia, neural tube defects …
[HTML][HTML] Endogenous H2S targets mitochondria to promote continual phagocytosis of erythrocytes by microglia after intracerebral hemorrhage
X Yan, M He, H Huang, Q Wang, Y Hu, X Wang, M Jin… - Redox Biology, 2022 - Elsevier
Hematoma clearance, which is achieved largely by phagocytosis of erythrocytes in the
hemorrhagic brain, limits injury and facilitates recovery following intracerebral hemorrhage …
hemorrhagic brain, limits injury and facilitates recovery following intracerebral hemorrhage …
[HTML][HTML] Hydrogen sulfide alleviates anxiety, motor, and cognitive dysfunctions in rats with maternal hyperhomocysteinemia via mitigation of oxidative stress
O Yakovleva, K Bogatova, R Mukhtarova, A Yakovlev… - Biomolecules, 2020 - mdpi.com
Hydrogen sulfide (H2S) is endogenously produced from sulfur containing amino acids,
including homocysteine and exerts neuroprotective effects. An increase of homocysteine …
including homocysteine and exerts neuroprotective effects. An increase of homocysteine …
[HTML][HTML] Endothelial progenitor cells dysfunctions and cardiometabolic disorders: from mechanisms to therapeutic approaches
AC Peyter, JB Armengaud, E Guillot… - International Journal of …, 2021 - mdpi.com
Metabolic syndrome (MetS) is a cluster of several disorders, such as hypertension, central
obesity, dyslipidemia, hyperglycemia, insulin resistance and non-alcoholic fatty liver …
obesity, dyslipidemia, hyperglycemia, insulin resistance and non-alcoholic fatty liver …
The complex interplay between DNA methylation and miRNAs in gene expression regulation
A Fuso, T Raia, M Orticello, M Lucarelli - Biochimie, 2020 - Elsevier
The short, non-coding RNAs, also called microRNAs (miRNAs) can bind complementary
sequences on cellular mRNAs. The consequence of this binding is generally the …
sequences on cellular mRNAs. The consequence of this binding is generally the …
Nitric oxide and hydrogen sulfide: Sibling rivalry in the family of epigenetic regulators
HP Kuschman, MB Palczewski, DD Thomas - Free Radical Biology and …, 2021 - Elsevier
Nitric oxide (NO) and hydrogen sulfide (H 2 S) were previously only known for their toxic
properties. Now they are regarded as potent gaseous messenger molecules …
properties. Now they are regarded as potent gaseous messenger molecules …
Hydrogen sulfide prevents the vascular dysfunction induced by severe traumatic brain injury in rats by reducing reactive oxygen species and modulating eNOS and …
FI López-Preza, SH de la Cruz, C Santiago-Castañeda… - Life Sciences, 2023 - Elsevier
Aim To assess the effects of subchronic administration with NaHS, an exogenous H 2 S
donor, on TBI-induced hypertension and vascular impairments. Main methods Animals …
donor, on TBI-induced hypertension and vascular impairments. Main methods Animals …