Plants produce a variety of high-value chemicals (eg, secondary metabolites) which have a
plethora of biological activities, which may be utilised in many facets of industry (eg …

Metabolomics is a branch of 'omics' sciences that utilises a couple of analytical tools for the
identification of small molecules (metabolites) in a given sample. The overarching goal of …

Modern research in food science and nutrition is moving from classical methodologies to
advanced analytical strategies in which MS‐based techniques play a crucial role. In this …

Mass spectrometry-based metabolome profiling became the method of choice in systems
biology approaches and aims to enhance biological understanding of complex biological …

Current clinical strategy for staging and prognostication of colorectal cancer (CRC) relies
mainly upon the TNM or Duke system. This clinicopathological stage is a crude prognostic …

Ion-exchange chromatography (IEC) is a chromatographic technique commonly used for the
separation of ions and ionizable molecules. Its direct coupling with mass spectrometry has …

The role of urinary metabolic profiling in systems biology research is expanding. This is
because of the use of this technology for clinical diagnostic and mechanistic studies and for …

Metabolic fingerprinting, the main tool in metabolomics, is a non-targeted methodology
where all detectable peaks (or signals), including those from unknown analytes, are …

Gas chromatography coupled to mass spectrometry is the most frequent tool for
metabolomic profiling of low molecular weight metabolites. Its suitability in health survey is …

The metabolome is the set of small molecular mass compounds found in biological media,
and metabolomics, which refers to as the analysis of metabolome in a given biological …