[HTML][HTML] Understanding chronic venous disease: a critical overview of its pathophysiology and medical management
MA Ortega, O Fraile-Martínez… - Journal of clinical …, 2021 - mdpi.com
Chronic venous disease (CVD) is a multifactorial condition affecting an important
percentage of the global population. It ranges from mild clinical signs, such as …
percentage of the global population. It ranges from mild clinical signs, such as …
Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses
Background The cause of multiple sclerosis is believed to involve environmental exposure
and genetic susceptibility. We aimed to summarise the environmental risk factors that have …
and genetic susceptibility. We aimed to summarise the environmental risk factors that have …
[HTML][HTML] An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice
A Sindrilaru, T Peters, S Wieschalka… - The Journal of …, 2011 - Am Soc Clin Investig
Uncontrolled macrophage activation is now considered to be a critical event in the
pathogenesis of chronic inflammatory diseases such as atherosclerosis, multiple sclerosis …
pathogenesis of chronic inflammatory diseases such as atherosclerosis, multiple sclerosis …
Iron metabolism in oligodendrocytes and astrocytes, implications for myelination and remyelination
Iron is a key nutrient for normal central nervous system (CNS) development and function;
thus, iron deficiency as well as iron excess may result in harmful effects in the CNS …
thus, iron deficiency as well as iron excess may result in harmful effects in the CNS …
Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis
P Zamboni, R Galeotti, E Menegatti… - Journal of Neurology …, 2009 - jnnp.bmj.com
Background: The extracranial venous outflow routes in clinically defined multiple sclerosis
(CDMS) have not previously been investigated. Methods: Sixty-five patients affected by …
(CDMS) have not previously been investigated. Methods: Sixty-five patients affected by …
[HTML][HTML] Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative …
DB Kell - BMC medical genomics, 2009 - Springer
Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …
[HTML][HTML] Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's …
DB Kell - Archives of toxicology, 2010 - Springer
Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …
death, often characterised by circumstances in which cells or tissues do not merely die and …
[HTML][HTML] Antimicrobial and wound healing properties of FeO fabricated chitosan/PVA nanocomposite sponge
A Sathiyaseelan, K Saravanakumar, AVA Mariadoss… - Antibiotics, 2021 - mdpi.com
Diabetic and anemia-associated diabetic wounds increase the considerable morbidity and
mortality in people, as reported by clinical studies. However, no anemia-associated diabetic …
mortality in people, as reported by clinical studies. However, no anemia-associated diabetic …
Characterizing iron deposition in multiple sclerosis lesions using susceptibility weighted imaging
EM Haacke, M Makki, Y Ge… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To investigate whether the variable forms of putative iron deposition seen with
susceptibility weighted imaging (SWI) will lead to a set of multiple sclerosis (MS) lesion …
susceptibility weighted imaging (SWI) will lead to a set of multiple sclerosis (MS) lesion …
[HTML][HTML] A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency
P Zamboni, R Galeotti, E Menegatti… - Journal of vascular …, 2009 - Elsevier
OBJECTIVE: Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
combined stenoses of the principal pathways of extracranial venous drainage, including the …
combined stenoses of the principal pathways of extracranial venous drainage, including the …