In a worldwide effort to generate clinically useful therapeutic or preventive interventions,
harnessing biophysical stimuli for directing cell fate is a powerful strategy. With the vision to …

Axial spondyloarthritis (AxSpA) is a chronic, inflammatory, autoimmune disease that
predominantly affects the joints of the spine, causes chronic pain, and, in advanced stages …

Mesenchymal stem cells (MSCs) are increasingly used as regenerative therapies for
patients in the preclinical and clinical phases of various diseases. However, the main …

Human bone marrow-derived multipotent mesenchymal stromal cells, often referred to as
mesenchymal stem cells (MSCs), represent an attractive cell source for many regenerative …

Human mesenchymal stem cells (hMSCs) are multipotent progenitor cells with the potential
to differentiate into various cell types, including osteoblasts, chondrocytes, and adipocytes …

Scaffold-based bone tissue engineering strategies fail to meet the clinical need to fabricate
patient-specific and defect shape-specific, anatomically relevant load-bearing bone …

Successful clinical translation of mesenchymal stromal cell (MSC) products has not been
achieved in the United States and may be in large part due to MSC functional heterogeneity …

Due to their immunomodulatory function, mesenchymal stromal cells (MSCs) are a
promising therapeutic with the potential to treat neuroinflammation associated with …

Precise quantification of cellular potential of stem cells, such as human bone marrow–
derived mesenchymal stem cells (hBMSCs), is important for achieving stable and effective …

Osteoporosis is a disease characterized by a decrease in bone mineral density, thereby
increasing the risk of sustaining a fragility fracture. Most medical therapies are systemic and …