Ischemic stroke is a leading cause of death worldwide. A key secondary cell death
mechanism mediating neurological damage following the initial episode of ischemic stroke …

Tissue repair and regeneration are thought to involve resident cell proliferation as well as
the selective recruitment of circulating stem and progenitor cell populations through complex …

Extramedullary hematopoiesis (EMH) is the expansion and differentiation of hematopoietic
stem and progenitor cells outside of the bone marrow. In postnatal life, as a compensatory …

Objectives: This study sought to assess of the mobilization of nonhematopoietic very small
embryonic-like stem cells (VSELs) in acute myocardial infarction (MI). Background: Acute MI …

Background and Purpose—In a murine model of stroke, we identified a population of very
small embryonic-like (VSEL) stem cells (SCs) in adult murine bone marrow that could be …

Evidence has accumulated that adult hematopoietic tissues and other organs contain a
population of dormant stem cells (SCs) that are more primitive than other, already restricted …

We have observed that conditioning for hematopoietic transplantation by lethal irradiation
induces a proteolytic microenvironment in the bone marrow (BM) that activates the …

Pluripotency is defined as the potential of a cell to differentiate into cells of the three germ
layers: endoderm, mesoderm and ectoderm. In vivo, the presence of pluripotent stem cells is …

Recently, we purified a population of CXCR4+/Oct‐4+/SSEA‐1+/Sca‐1+/Lin−/CD45− very
small embryonic‐like stem cells (VSELs) from adult murine bone marrow (BM). After using …

One of the most intriguing questions in stem cell biology is whether pluripotent stem cells
exist in adult tissues. Several groups of investigators employing i) various isolation …