Isolation and characterization of exosomes for cancer research

L Zhu, HT Sun, S Wang, SL Huang, Y Zheng… - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …

[HTML][HTML] Exosome detection via surface-enhanced Raman spectroscopy for cancer diagnosis

J Li, Y Li, P Li, Y Zhang, L Du, Y Wang, C Zhang… - Acta biomaterialia, 2022 - Elsevier
As nanoscale extracellular vesicles, exosomes are secreted by various cell types, and they
are widely distributed in multiple biological fluids. Studies have shown that tumor-derived …

Multi-omic analyses of changes in the tumor microenvironment of pancreatic adenocarcinoma following neoadjuvant treatment with anti-PD-1 therapy

K Li, JA Tandurella, J Gai, Q Zhu, SJ Lim, DL Thomas… - Cancer Cell, 2022 - cell.com
Successful pancreatic ductal adenocarcinoma (PDAC) immunotherapy necessitates
optimization and maintenance of activated effector T cells (Teff). We prospectively collected …

Upconversion nanoparticles for super-resolution quantification of single small extracellular vesicles

G Huang, Y Liu, D Wang, Y Zhu, S Wen, J Ruan, D Jin - ELight, 2022 - Springer
Although small EVs (sEVs) have been used widely as biomarkers in disease diagnosis, their
heterogeneity at single EV level has rarely been revealed. This is because high-resolution …

The functional and clinical roles of liquid biopsy in patient-derived models

Z Zhu, E Hu, H Shen, J Tan, S Zeng - Journal of Hematology & Oncology, 2023 - Springer
The liquid biopsy includes the detection of circulating tumor cells (CTCs) and CTC clusters
in blood, as well as the detection of, cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA) …

Global trend in exosome isolation and application: an update concept in management of diseases

M Omrani, H Beyrampour-Basmenj… - Molecular and Cellular …, 2024 - Springer
Extracellular vesicles (EVs) secreted by various cells offer great potential for use in the
diagnosis and treatment of disease. EVs are heterogeneous membranous vesicles …

Exosome-mediated crosstalk between tumor and tumor-associated macrophages

Q Chen, Y Li, W Gao, L Chen, W Xu… - Frontiers in Molecular …, 2021 - frontiersin.org
Exosomes are nanosized vesicles, derived from the endolysosomal compartment of cells
and can shuttle diverse biomolecules such as nucleic acids, proteins, lipids, amino acids …

SERS resolving of the significance of acetate on the enhanced catalytic activity of nanozymes

Q Zhao, H Wang, W Jiang, H Gao, S Wen… - Analytical …, 2022 - ACS Publications
Understanding the structure–activity correlation and reaction mechanism of the catalytic
process in an acetic acid–sodium acetate (HAc-NaAc) buffer environment is crucial for the …

Harnessing exosomes as cancer biomarkers in clinical oncology

S Ghosh, RL Rajendran, AA Mahajan… - Cancer Cell …, 2024 - Springer
Exosomes are extracellular vesicles well known for facilitating cell-to-cell communication by
distributing essential macromolecules like proteins, DNA, mRNA, lipids, and miRNA. These …

SERS-Based Droplet Microfluidic Platform for Sensitive and High-Throughput Detection of Cancer Exosomes

KHW Ho, H Lai, R Zhang, H Chen, W Yin, X Yan… - ACS …, 2024 - ACS Publications
Exosomes, nanosized extracellular vesicles containing biomolecular cargo, are increasingly
recognized as promising noninvasive biomarkers for cancer diagnosis, particularly for their …