Metabolic theory of preeclampsia: Implications for maternal cardiovascular health
MM Manoharan, GC Montes… - American Journal …, 2024 - journals.physiology.org
Preeclampsia (PE) is a multisystemic disorder of pregnancy that not only causes perinatal
mortality and morbidity but also has a long-term toll on the maternal and fetal cardiovascular …
mortality and morbidity but also has a long-term toll on the maternal and fetal cardiovascular …
10. Role of high dimensional technology in preeclampsia (omics in preeclampsia)
L Youssef, L Testa, F Crovetto, F Crispi - Best Practice & Research Clinical …, 2024 - Elsevier
Preeclampsia is a pregnancy-specific disease that has no known precise cause. Integrative
biology approach based on multi-omics has been applied to identify upstream pathways and …
biology approach based on multi-omics has been applied to identify upstream pathways and …
Proteomics and metabolomics profiling of platelets and plasma mediators of thrombo-inflammation in gestational hypertension and preeclampsia
LGN de Almeida, D Young, L Chow, J Nicholas, A Lee… - Cells, 2022 - mdpi.com
Platelets may be pivotal mediators of the thrombotic and coagulopathic complications of
preeclampsia (PE), linking inflammation and thrombosis with endothelial and vascular …
preeclampsia (PE), linking inflammation and thrombosis with endothelial and vascular …
Growth-Restricted Fetuses and Offspring Reveal Adverse Sex-Specific Metabolic Responses in Preeclamptic Mice Expressing Human sFLT1
R Vogtmann, M Bao, MV Dewan, A Riedel… - International Journal of …, 2023 - mdpi.com
Fetal adaptations to harmful intrauterine environments due to pregnancy disorders such as
preeclampsia (PE) can negatively program the offspring's metabolism, resulting in long-term …
preeclampsia (PE) can negatively program the offspring's metabolism, resulting in long-term …
Adipokine chemerin overexpression in trophoblasts leads to dyslipidemia in pregnant mice: implications for preeclampsia
L Tan, Z Ouyang, Z Chen, F Sun, H Guo… - Lipids in Health and …, 2023 - Springer
Background The adipokine chemerin regulates adipogenesis and the metabolic function of
both adipocytes and liver. Chemerin is elevated in preeclamptic women, and …
both adipocytes and liver. Chemerin is elevated in preeclamptic women, and …
Predicting the onset of preeclampsia by longitudinal monitoring of metabolic changes throughout pregnancy with Raman spectroscopy
Preeclampsia is a life‐threatening pregnancy disorder. Current clinical assays cannot
predict the onset of preeclampsia until the late 2nd trimester, which often leads to poor …
predict the onset of preeclampsia until the late 2nd trimester, which often leads to poor …
First-trimester preterm preeclampsia prediction with metabolite biomarkers: differential prediction according to maternal body mass index
Background Prediction of preeclampsia risk is key to informing effective maternal care.
Current screening for preeclampsia at 11 to 13 weeks of gestation using maternal …
Current screening for preeclampsia at 11 to 13 weeks of gestation using maternal …
Comprehensive microarray analysis of severe preeclampsia placenta to identify differentially expressed genes, biological pathways, hub genes, and their related non …
Introduction Preeclampsia (PE) is a serious pregnancy-related complication caused by high
blood pressure in pregnant women. The severe form has more devastating effects …
blood pressure in pregnant women. The severe form has more devastating effects …
Metabolic dynamics and prediction of sFGR and adverse fetal outcomes: a prospective longitudinal cohort study
N Huang, W Chen, H Jiang, J Yang, Y Zhang, H Shi… - BMC medicine, 2023 - Springer
Background Selective fetal growth restriction (sFGR) is an extreme complication that
significantly increases the risk of perinatal mortality and long-term adverse neurological …
significantly increases the risk of perinatal mortality and long-term adverse neurological …
Plasma metabolic profile reveals signatures of maternal health during gestational hypertension and preeclampsia without and with severe features
Preeclampsia, a pregnancy-specific syndrome, poses substantial risks to maternal and
neonatal health, particularly in cases with severe features. Our study focuses on evaluating …
neonatal health, particularly in cases with severe features. Our study focuses on evaluating …