Nutraceuticals and cancer: Potential for natural polyphenols

J Maiuolo, M Gliozzi, C Carresi, V Musolino… - Nutrients, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, associated with multifactorial
pathophysiological components. In particular, genetic mutations, infection or inflammation …

Curcumin as an anti‐inflammatory agent: Implications to radiotherapy and chemotherapy

B Farhood, K Mortezaee, NH Goradel… - Journal of cellular …, 2019 - Wiley Online Library
Cancer is the second cause of death worldwide. Chemotherapy and radiotherapy are the
most common modalities for the treatment of cancer. Experimental studies have shown that …

Receptor tyrosine kinases and their signaling pathways as therapeutic targets of curcumin in cancer

S Sudhesh Dev, SA Zainal Abidin… - Frontiers in …, 2021 - frontiersin.org
Receptor tyrosine kinases (RTKs) are transmembrane cell-surface proteins that act as signal
transducers. They regulate essential cellular processes like proliferation, apoptosis …

Curcumin activates the Nrf2 pathway and induces cellular protection against oxidative injury

M Ashrafizadeh, Z Ahmadi… - Current Molecular …, 2020 - ingentaconnect.com
Curcumin is a naturally occurring polyphenol that is isolated from the rhizome of Curcuma
longa (turmeric). This medicinal compound has different biological activities, including …

[HTML][HTML] Natural products as safeguards against monosodium glutamate-induced toxicity

MM Hajihasani, V Soheili, MR Zirak… - Iranian Journal of …, 2020 - ncbi.nlm.nih.gov
Monosodium glutamate is a sodium salt of a nonessential amino acid, L-glutamic acid,
which is widely used in food industry. Glutamate plays an important role in principal brain …

Biological properties of metal complexes of curcumin

A Shakeri, Y Panahi, TP Johnston, A Sahebkar - BioFactors, 2019 - Wiley Online Library
Curcumin, a naturally occurring phenolic compound isolated from Curcuma longa, has
different pharmacological effects, including antiinflammatory, antimicrobial, antioxidant, and …

Dendrimers as nanocarriers for the delivery of drugs obtained from natural products

H An, X Deng, F Wang, P Xu, N Wang - Polymers, 2023 - mdpi.com
Natural products have proven their value as drugs that can be therapeutically beneficial in
the treatment of various diseases. However, most natural products have low solubility and …

Effects of curcumin on microglial cells

F Ghasemi, H Bagheri, GE Barreto, MI Read… - Neurotoxicity …, 2019 - Springer
Microglia are innate immune system cells which reside in the central nervous system (CNS).
Resting microglia regulate the homeostasis of the CNS via phagocytic activity to clear …

The role of curcumin/curcuminoids during gastric cancer chemotherapy: a systematic review of non-clinical study

M Najafi, K Mortezaee, M Rahimifard, B Farhood… - Life sciences, 2020 - Elsevier
Aims Chemotherapy is an effective therapeutic modality which is commonly used for battling
various cancers. However, several side effects induced by chemotherapeutic drugs would …

Anti-MRSA activity of curcumin in planktonic cells and biofilms and determination of possible action mechanisms

JB de Andrade Neto, VP de Farias Cabral… - Microbial …, 2021 - Elsevier
Staphylococcus aureus is a commensal bacterium and opportunistic human pathogen that
can cause a wide variety of clinical infections. It is recognized for its ability to acquire …