Recent advances in nanozymes: from matters to bioapplications

Y Ai, ZN Hu, X Liang, H Sun, H Xin… - Advanced Functional …, 2022 - Wiley Online Library
The manufacture of bionic materials to simulate the natural counterparts has attracted
extensive attention. As one of the subcategories of biomimetic materials, the development of …

Challenges and opportunities for the next generation of cardiovascular tissue engineering

S Cho, DE Discher, KW Leong, G Vunjak-Novakovic… - Nature …, 2022 - nature.com
Engineered cardiac tissues derived from human induced pluripotent stem cells offer unique
opportunities for patient-specific disease modeling, drug discovery and cardiac repair. Since …

[HTML][HTML] Inhibition of fatty acid oxidation enables heart regeneration in adult mice

X Li, F Wu, S Günther, M Looso, C Kuenne, T Zhang… - Nature, 2023 - nature.com
Postnatal maturation of cardiomyocytes is characterized by a metabolic switch from
glycolysis to fatty acid oxidation, chromatin reconfiguration and exit from the cell cycle …

[HTML][HTML] Telomeres: history, health, and hallmarks of aging

D Chakravarti, KA LaBella, RA DePinho - Cell, 2021 - cell.com
The escalating social and economic burden of an aging world population has placed aging
research at center stage. The hallmarks of aging comprise diverse molecular mechanisms …

Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

X Zhu, Z Chen, W Shen, G Huang, JM Sedivy… - Signal transduction and …, 2021 - nature.com
Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine

E Karbassi, A Fenix, S Marchiano, N Muraoka… - Nature Reviews …, 2020 - nature.com
Our knowledge of pluripotent stem cell (PSC) biology has advanced to the point where we
now can generate most cells of the human body in the laboratory. PSC-derived …

Cardiomyocyte maturation: new phase in development

Y Guo, WT Pu - Circulation research, 2020 - Am Heart Assoc
Maturation is the last phase of heart development that prepares the organ for strong,
efficient, and persistent pumping throughout the mammal's lifespan. This process is …

ROS and diseases: Role in metabolism and energy supply

S Yang, G Lian - Molecular and cellular biochemistry, 2020 - Springer
Researches dedicated to reactive oxygen species (ROS) had been performed for decades,
yet the outcomes remain controversial. With the relentless effort of studies, researchers have …

Cellular aging beyond cellular senescence: Markers of senescence prior to cell cycle arrest in vitro and in vivo

M Ogrodnik - Aging cell, 2021 - Wiley Online Library
The field of research on cellular senescence experienced a rapid expansion from being
primarily focused on in vitro aspects of aging to the vast territories of animal and clinical …

Regenerative capacity of adipose derived stem cells (ADSCs), comparison with mesenchymal stem cells (MSCs)

L Mazini, L Rochette, M Amine, G Malka - International journal of …, 2019 - mdpi.com
Adipose tissue is now on the top one of stem cell sources regarding its accessibility,
abundance, and less painful collection procedure when compared to other sources. The …