[HTML][HTML] Sympathetic nervous system activation and heart failure: Current state of evidence and the pathophysiology in the light of novel biomarkers

JA Borovac, D D'Amario, J Bozic… - World journal of …, 2020 - ncbi.nlm.nih.gov
Heart failure (HF) is a complex clinical syndrome characterized by the activation of at least
several neurohumoral pathways that have a common role in maintaining cardiac output and …

Autonomic modulation for cardiovascular disease

J Hadaya, JL Ardell - Frontiers in physiology, 2020 - frontiersin.org
Dysfunction of the autonomic nervous system has been implicated in the pathogenesis of
cardiovascular disease, including congestive heart failure and cardiac arrhythmias. Despite …

Clinical neurocardiology defining the value of neuroscience‐based cardiovascular therapeutics

K Shivkumar, OA Ajijola, I Anand… - The Journal of …, 2016 - Wiley Online Library
The autonomic nervous system regulates all aspects of normal cardiac function, and is
recognized to play a critical role in the pathophysiology of many cardiovascular diseases. As …

The role of neuropeptide Y in cardiovascular health and disease

CMJ Tan, P Green, N Tapoulal… - Frontiers in …, 2018 - frontiersin.org
Neuropeptide Y (NPY) is an abundant sympathetic co-transmitter, widely found in the central
and peripheral nervous systems and with diverse roles in multiple physiological processes …

Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

The intrinsic cardiac nervous system and its role in cardiac pacemaking and conduction

L Fedele, T Brand - Journal of cardiovascular development and disease, 2020 - mdpi.com
The cardiac autonomic nervous system (CANS) plays a key role for the regulation of cardiac
activity with its dysregulation being involved in various heart diseases, such as cardiac …

Efficacy of stellate ganglion blockade in managing electrical storm: a systematic review

L Meng, CH Tseng, K Shivkumar, O Ajijola - JACC: Clinical …, 2017 - jacc.org
Objectives: The study sought to characterize the efficacy of stellate ganglion block (SGB) as
a treatment for electrical storm (ES). Background: The efficacy of percutaneous SGB for …

Prospective study of epigenetic age acceleration and incidence of cardiovascular disease outcomes in the ARIC study (Atherosclerosis Risk in Communities)

NS Roetker, JS Pankow, J Bressler… - Circulation: Genomic …, 2018 - Am Heart Assoc
Background: DNA methylation-based patterns of biological aging, known as epigenetic age
acceleration, are predictive of all-cause mortality, but little is known about their association …

The role of the autonomic nervous system in cardiac arrhythmias: the neuro-cardiac axis, more foe than friend?

AA Manolis, TA Manolis, EJ Apostolopoulos… - Trends in cardiovascular …, 2021 - Elsevier
The autonomic nervous system (ANS) with its two limbs, the sympathetic (SNS) and
parasympathetic nervous system (PSNS), plays a critical role in the modulation of cardiac …

Autonomic cardiac innervation: development and adult plasticity

W Hasan - Organogenesis, 2013 - Taylor & Francis
Autonomic cardiac neurons have a common origin in the neural crest but undergo distinct
developmental differentiation as they mature toward their adult phenotype. Progenitor cells …