The role of m6A modification in the biological functions and diseases
X Jiang, B Liu, Z Nie, L Duan, Q Xiong, Z Jin… - Signal transduction and …, 2021 - nature.com
Abstract N6-methyladenosine (m6A) is the most prevalent, abundant and conserved internal
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
The role of m6A, m5C and Ψ RNA modifications in cancer: Novel therapeutic opportunities
RNA modifications have recently emerged as critical posttranscriptional regulators of gene
expression programmes. Significant advances have been made in understanding the …
expression programmes. Significant advances have been made in understanding the …
The interplay between m6A RNA methylation and noncoding RNA in cancer
S Ma, C Chen, X Ji, J Liu, Q Zhou, G Wang… - Journal of hematology & …, 2019 - Springer
Abstract N6-methyladenosine (m6A) methylation, one of the most common RNA
modifications, has been reported to execute important functions that affect normal life …
modifications, has been reported to execute important functions that affect normal life …
[HTML][HTML] The role of m6A RNA methylation in cancer
T Sun, R Wu, L Ming - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstract N6-methyladenosine (m6A), the most abundant internal modification of RNA in
eukaryotic cells, has gained increasing attention in recent years. The m6A modification …
eukaryotic cells, has gained increasing attention in recent years. The m6A modification …
N6-methyladenosine methyltransferases: functions, regulation, and clinical potential
W Huang, TQ Chen, K Fang, ZC Zeng, H Ye… - Journal of Hematology & …, 2021 - Springer
Abstract N6-methyladenosine (m6A) has emerged as an abundant modification throughout
the transcriptome with widespread functions in protein-coding and noncoding RNAs. It …
the transcriptome with widespread functions in protein-coding and noncoding RNAs. It …
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
Abstract N 6-methyladenosine (m6A) is an abundant nucleotide modification in mRNA that is
required for the differentiation of mouse embryonic stem cells. However, it remains unknown …
required for the differentiation of mouse embryonic stem cells. However, it remains unknown …
RNA demethylase ALKBH5 selectively promotes tumorigenesis and cancer stem cell self-renewal in acute myeloid leukemia
Summary N 6-methyladenosine (m 6 A), the most abundant internal modification in mRNA,
has been implicated in tumorigenesis. As an m 6 A demethylase, ALKBH5 has been shown …
has been implicated in tumorigenesis. As an m 6 A demethylase, ALKBH5 has been shown …
RNA N6-methyladenosine modification in cancers: current status and perspectives
Abstract N 6-methyladenosine (m6A), the most abundant internal modification in eukaryotic
messenger RNAs (mRNAs), has been shown to play critical roles in various normal …
messenger RNAs (mRNAs), has been shown to play critical roles in various normal …
Aberrations of m6A regulators are associated with tumorigenesis and metastasis in head and neck squamous cell carcinoma
P Arumugam, R George, VP Jayaseelan - Archives of oral biology, 2021 - Elsevier
Abstract Objective N6-Methyladenosine (m6A) is the most common RNA modification in
eukaryotic mRNAs and growing evidence suggests that m6A modification and its regulators …
eukaryotic mRNAs and growing evidence suggests that m6A modification and its regulators …
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl (2) d
P Knuckles, T Lence, IU Haussmann… - Genes & …, 2018 - genesdev.cshlp.org
Abstract N 6-methyladenosine (m 6 A) is the most abundant mRNA modification in
eukaryotes, playing crucial roles in multiple biological processes. m 6 A is catalyzed by the …
eukaryotes, playing crucial roles in multiple biological processes. m 6 A is catalyzed by the …