Estrogen signaling and cardiovascular disease
E Murphy - Circulation research, 2011 - Am Heart Assoc
Estrogen has pleiotropic effects on the cardiovascular system. The mechanisms by which
estrogen confers these pleiotropic effects are undergoing active investigation. Until a …
estrogen confers these pleiotropic effects are undergoing active investigation. Until a …
Does GPER Really Function as a G Protein-Coupled Estrogen Receptor in vivo?
J Luo, D Liu - Frontiers in endocrinology, 2020 - frontiersin.org
Estrogen can elicit pleiotropic cellular responses via a diversity of estrogen receptors (ERs)—
mediated genomic and rapid non-genomic mechanisms. Unlike the genomic responses …
mediated genomic and rapid non-genomic mechanisms. Unlike the genomic responses …
The expanding complexity of estrogen receptor signaling in the cardiovascular system
S Menazza, E Murphy - Circulation research, 2016 - Am Heart Assoc
Estrogen has important effects on cardiovascular function including regulation of vascular
function, blood pressure, endothelial relaxation, and the development of hypertrophy and …
function, blood pressure, endothelial relaxation, and the development of hypertrophy and …
Cold-activated brown fat-derived extracellular vesicle-miR-378a-3p stimulates hepatic gluconeogenesis in male mice
J Xu, L Cui, J Wang, S Zheng, H Zhang, S Ke… - Nature …, 2023 - nature.com
During cold exposure, activated brown adipose tissue (BAT) takes up a large amount of
circulating glucose to fuel non-shivering thermogenesis and defend against hypothermia …
circulating glucose to fuel non-shivering thermogenesis and defend against hypothermia …
WNT signaling in pre-granulosa cells is required for ovarian folliculogenesis and female fertility
O Habara, CY Logan, M Kanai-Azuma… - …, 2021 - journals.biologists.com
In mammalian ovaries, immature oocytes are reserved in primordial follicles until their
activation for potential ovulation. Precise control of primordial follicle activation (PFA) is …
activation for potential ovulation. Precise control of primordial follicle activation (PFA) is …
Sex differences in cardiac electrophysiology and clinical arrhythmias: epidemiology, therapeutics, and mechanisms
Sex differences in cardiac electrophysiological properties and arrhythmias are evident in
epidemiologic and investigative studies as well as in daily patient care. At the …
epidemiologic and investigative studies as well as in daily patient care. At the …
The link between sex hormones and susceptibility to cardiac arrhythmias: from molecular basis to clinical implications
S Costa, AM Saguner, A Gasperetti, D Akdis… - Frontiers in …, 2021 - frontiersin.org
It is well-known that gender is an independent risk factor for some types of cardiac
arrhythmias. For example, males have a greater prevalence of atrial fibrillation and the …
arrhythmias. For example, males have a greater prevalence of atrial fibrillation and the …
Sex hormones and the QT interval: a review
T Sedlak, C Shufelt, C Iribarren… - Journal of women's …, 2012 - liebertpub.com
A prolonged QT interval is a marker for an increased risk of ventricular tachyarrhythmias.
Both endogenous and exogenous sex hormones have been shown to affect the QT interval …
Both endogenous and exogenous sex hormones have been shown to affect the QT interval …
Sex differences in mechanisms of cardiac excitation–contraction coupling
RJ Parks, SE Howlett - Pflügers Archiv-European Journal of Physiology, 2013 - Springer
The incidence and expression of cardiovascular diseases differs between the sexes. This is
not surprising, as cardiac physiology differs between men and women. Clinical and basic …
not surprising, as cardiac physiology differs between men and women. Clinical and basic …
Sensory neurons, neuroimmunity, and pain modulation by sex hormones
The inclusion of women in preclinical pain studies has become more commonplace in the
last decade as the National Institutes of Health (NIH) released its “Sex as a Biological …
last decade as the National Institutes of Health (NIH) released its “Sex as a Biological …