[HTML][HTML] Gram-negative neonatal sepsis in low-and lower-middle-income countries and WHO empirical antibiotic recommendations: A systematic review and meta …
Background Neonatal sepsis is a significant global health issue associated with marked
regional disparities in mortality. Antimicrobial resistance (AMR) is a growing concern in …
regional disparities in mortality. Antimicrobial resistance (AMR) is a growing concern in …
Reviewing the WHO guidelines for antibiotic use for sepsis in neonates and children
A Fuchs, J Bielicki, S Mathur, M Sharland… - Paediatrics and …, 2018 - Taylor & Francis
Background Guidelines from 2005 for treating suspected sepsis in low-and middle-income
countries (LMIC) recommended hospitalisation and prophylactic intramuscular (IM) or …
countries (LMIC) recommended hospitalisation and prophylactic intramuscular (IM) or …
[HTML][HTML] Patterns of antibiotic use, pathogens, and prediction of mortality in hospitalized neonates and young infants with sepsis: A global neonatal sepsis …
NJ Russell, W Stöhr, N Plakkal, A Cook… - PLoS …, 2023 - journals.plos.org
Background There is limited data on antibiotic treatment in hospitalized neonates in low-and
middle-income countries (LMICs). We aimed to describe patterns of antibiotic use …
middle-income countries (LMICs). We aimed to describe patterns of antibiotic use …
[HTML][HTML] Causes and incidence of community-acquired serious infections among young children in south Asia (ANISA): an observational cohort study
SK Saha, SJ Schrag, S El Arifeen, LC Mullany… - The Lancet, 2018 - thelancet.com
Background More than 500 000 neonatal deaths per year result from possible serious
bacterial infections (pSBIs), but the causes are largely unknown. We investigated the …
bacterial infections (pSBIs), but the causes are largely unknown. We investigated the …
Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin–clavulanic acid) versus a full course of intravenous antibiotics in neonates with …
FM Keij, RF Kornelisse, NG Hartwig… - The Lancet Child & …, 2022 - thelancet.com
Background Switching from intravenous antibiotic therapy to oral antibiotic therapy among
neonates is not yet practised in high-income settings due to uncertainties about exposure …
neonates is not yet practised in high-income settings due to uncertainties about exposure …
Antibiotic regimens for late‐onset neonatal sepsis
Background Neonatal sepsis is a major cause of morbidity and mortality. It is the third
leading cause of neonatal mortality globally constituting 13% of overall neonatal mortality …
leading cause of neonatal mortality globally constituting 13% of overall neonatal mortality …
[HTML][HTML] Managing possible serious bacterial infection of young infants where referral is not possible: Lessons from the early implementation experience in Kushtia …
Background Serious infections account for 25% of global newborn deaths annually, most in
low-resource settings where hospital-based treatment is not accessible or feasible. In …
low-resource settings where hospital-based treatment is not accessible or feasible. In …
Antibiotic regimens for early‐onset neonatal sepsis
Background Neonatal sepsis is a major cause of morbidity and mortality. It is the third
leading cause of neonatal mortality globally constituting 13% of overall neonatal mortality …
leading cause of neonatal mortality globally constituting 13% of overall neonatal mortality …
[HTML][HTML] WHO's essential medicines and AWaRe: recommendations on first-and second-choice antibiotics for empiric treatment of clinical infections
Abstract The WHO Model List of Essential Medicines (EML) prioritizes medicines that have
significant global public health value. The EML can also deliver important messages on …
significant global public health value. The EML can also deliver important messages on …
[HTML][HTML] Lessons from implementation research on community management of Possible Serious Bacterial Infection (PSBI) in young infants (0-59 days), when the …
R Mukhopadhyay, NK Arora, PK Sharma, S Dalpath… - PloS one, 2021 - journals.plos.org
Background Neonatal sepsis is a major cause of death in India, which needs hospital
management but many families cannot access hospitals. The World Health Organization …
management but many families cannot access hospitals. The World Health Organization …