Cell surface mucins are large transmembrane glycoproteins involved in diverse functions
ranging from shielding the airway epithelium against pathogenic infection to regulating …

Mucins are high-molecular weight glycoproteins characterized by their extensive O-
glycosylation. Major mucins expressed by the ocular surface epithelia include cell surface …

Conclusions The lung interfaces with the environment across a continuous and
heterogeneous epithelium. The proximal conducting airways are lined with a …

The characteristics and possible functions of the most abundant proteins associated with the
bovine milk-fat globule membrane are reviewed. Under the auspices of the Milk Protein …

MUC1 is a large (> 400 kDa), heavily glycosylated transmembrane protein that is aberrantly
expressed on greater than 90% of human breast carcinomas and subsequent metastases …

For more than a decade, tumor immunologists have focused their efforts on discovering
tumor-associated antigens, as a first step toward the design of an effective cancer vaccine …

Mucin glycoproteins are major constituents of the glycocalyx that covers mucosal epithelium.
Two broad classes of mucins exist: membrane-associated and secretory. Of the secreted …

Alteration of protein trafficking and localization is associated with several diseases, including
cystic fibrosis, breast cancer, colorectal cancer, leukemia and diabetes. Specifically …

Mucins are high molecular weight glycoproteins that provide a protective layer on epithelial
surfaces and are involved in cell–cell interactions, signaling, and metastasis. The …

There are 3 major forms of autosomal dominant tubulointerstitial kidney disease (ADTKD):
ADTKD due to UMOD mutations, MUC1 mutations, and mutations in the REN gene …