The brain is arguably the most complex organ. The branched and extended morphology of
nerve cells, their subcellular complexity, the multiplicity of brain cell types as well as their …

The neurotransmitters glutamate and γ-aminobutyric acid (GABA) transmit synaptic signals
by activating fast-acting ligand-gated ion channels and more slowly acting G-protein …

GABAB receptors (GBRs) are key regulators of synaptic release but little is known about
trafficking mechanisms that control their presynaptic abundance. We now show that …

The structural and functional plasticity of synapses is critical for learning and memory. Long-
term potentiation (LTP) induction promotes spine growth and AMPAR accumulation at …

Action potential-evoked neurotransmitter release is impaired in knock-out neurons lacking
synaptic cell-adhesion molecules α-neurexins (αNrxns), the extracellularly longer variants of …

Abstract GABA A receptors (GABA A Rs) are the principal inhibitory neurotransmitter
receptors in the central nervous system. They control neuronal excitability by synaptic and …

GABAB receptors (GBRs), the G protein‐coupled receptors for the neurotransmitter γ‐
aminobutyric acid (GABA), regulate synaptic transmission at most synapses in the brain …

The behavioral and anatomical deficits seen in fragile X syndrome (FXS) are widely
believed to result from imbalances in the relative strengths of excitatory and inhibitory …

Abstract γ-Aminobutyric acid B receptors (GABABRs) are broadly expressed throughout the
central nervous system where they play an important role in regulating neuronal excitability …

Over the last decade, developments in single molecule imaging have changed our vision of
synaptic physiology. By providing high spatio-temporal resolution maps of the molecular …