The kidney is a highly complex organ in the human body. Although creating an in vitro
model of the human kidney is challenging, tremendous advances have been made in recent …

Current kidney organoids model development and diseases of the nephron but not the
contiguous epithelial network of the kidney's collecting duct (CD) system. Here, we report the …

Renal disorders are an emerging global public health issue with a higher growth rate
despite progress in supportive therapies. In order to find more promising treatments to …

Investigations into bioengineering kidneys have been extensively conducted owing to their
potential for preclinical assays and regenerative medicine. Various approaches and …

The majority of nucleated somatic cells can be reprogrammed to induced pluripotent stem
cells (iPSCs). The process of reprogramming involves epigenetic remodelling to turn on …

Abstract The Schlafen (Slfn) family proteins are critical regulators of cell proliferation,
induction of immune responses, differentiation, self-restoration, and cell cycle progression …

慢性肾疾病具有高发病率, 高致死率的特点并且在全球范围内流行, 但除了血液透析和肾移植外,
迄今尚无其他有效方法治愈, 因此是当前严重危害人类生命健康的重大疾病之一 …

Endothelial cells (ECs) across ages and tissues are highly heterogeneous in developmental
origins, structures, functions, and cellular plasticity. Here, we applied CoBATCH for single …

Résumé A corticosurrénale (CS) est un organe central stéroïdogénique qui joue un rôle clé
dans le maintien de l'homéostasie de l'organisme. Plusieurs maladies des surrénales (par …

The adrenal cortex (AC) is a central steroidogenic organ with key functions in maintaining
body homeostasis. Several adrenal diseases (eg Congenital adrenal hyperplasia (CAH)) …