Genetic and genomic approaches have implicated hundreds of genetic loci in
neurodevelopmental disorders and neurodegeneration, but mechanistic understanding …

The current development of nanobiotechnologies requires a better understanding of cell–
surface interactions on the nanometre scale. Recently, advances in nanoscale patterning …

Abstract Background Transcriptional studies suggest Alzheimer's disease (AD) involves
dysfunction of many cellular pathways, including synaptic transmission, cytoskeletal …

Neuroplasticity involves molecular and structural changes in central nervous system (CNS)
throughout life. The concept of neural organization allows for remodeling as a compensatory …

A major challenge in neuronal stem cell biology lies in characterization of lineage-specific
reprogrammed human neuronal cells, a process that necessitates the use of an assay …

Gene microarrays may enable the elucidation of neurobiological changes underlying the
pathophysiology and treatment of major depression. However, previous studies of …

Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …

Gene expression changes in neuropsychiatric and neurodegenerative disorders, and gene
responses to therapeutic drugs, provide new ways to identify central nervous system (CNS) …

During development of the central nervous system (CNS), cycling uncommitted progenitor
cells give rise to a variety of distinct neuronal and glial cell types. As these different cell types …

Research indicates that female risk of developing Alzheimer's disease (AD) is greater than
that of males. Moderate reduction of calorie intake, known as calorie restriction (CR) …