Uncultivated microbes in need of their own taxonomy

KT Konstantinidis, R Rosselló-Móra… - The ISME journal, 2017 - academic.oup.com
The great majority of microbial species remains uncultured, severely limiting their taxonomic
characterization and thus communication among scientists. Although Candidatus was …

Opposite Sides of Pantoea agglomerans and Its Associated Commercial Outlook

AS Lorenzi, ML Bonatelli, MA Chia, L Peressim… - Microorganisms, 2022 - mdpi.com
Multifaceted microorganisms such as the bacterium Pantoea colonize a wide range of
habitats and can exhibit both beneficial and harmful behaviors, which provide new insights …

Introducing EzAAI: a pipeline for high throughput calculations of prokaryotic average amino acid identity

D Kim, S Park, J Chun - Journal of Microbiology, 2021 - Springer
The average amino acid identity (AAI) is an index of pairwise genomic relatedness, and
multiple studies have proposed its application in prokaryotic taxonomy and related …

A catalogue of 1,167 genomes from the human gut archaeome

CM Chibani, A Mahnert, G Borrel, A Almeida… - Nature …, 2022 - nature.com
The human gut microbiome plays an important role in health, but its archaeal diversity
remains largely unexplored. In the present study, we report the analysis of 1,167 …

High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries

C Jain, LM Rodriguez-R, AM Phillippy… - Nature …, 2018 - nature.com
A fundamental question in microbiology is whether there is continuum of genetic diversity
among genomes, or clear species boundaries prevail instead. Whole-genome similarity …

Lactobacillus reuteri tryptophan metabolism promotes host susceptibility to CNS autoimmunity

TL Montgomery, K Eckstrom, KH Lile, S Caldwell… - Microbiome, 2022 - Springer
Background Dysregulation of gut microbiota-associated tryptophan metabolism has been
observed in patients with multiple sclerosis. However, defining direct mechanistic links …

The Microbial Genomes Atlas (MiGA) webserver: taxonomic and gene diversity analysis of Archaea and Bacteria at the whole genome level

LM Rodriguez-R, S Gunturu, WT Harvey… - Nucleic acids …, 2018 - academic.oup.com
The small subunit ribosomal RNA gene (16S rRNA) has been successfully used to
catalogue and study the diversity of prokaryotic species and communities but it offers limited …

Characterization of crAss-like phage isolates highlights Crassvirales genetic heterogeneity and worldwide distribution

MD Ramos-Barbero, C Gómez-Gómez… - Nature …, 2023 - nature.com
Crassvirales (crAss-like phages) are an abundant group of human gut-specific
bacteriophages discovered in silico. The use of crAss-like phages as human fecal indicators …

The reliability of metagenome-assembled genomes (MAGs) in representing natural populations: insights from comparing MAGs against isolate genomes derived from …

A Meziti, LM Rodriguez-R, JK Hatt… - Applied and …, 2021 - Am Soc Microbiol
The recovery of metagenome-assembled genomes (MAGs) from metagenomic data has
recently become a common task for microbial studies. The strengths and limitations of the …

Genomic insights into the Acidobacteria reveal strategies for their success in terrestrial environments

SA Eichorst, D Trojan, S Roux… - Environmental …, 2018 - Wiley Online Library
Members of the phylum Acidobacteria are abundant and ubiquitous across soils. We
performed a large‐scale comparative genome analysis spanning subdivisions 1, 3, 4, 6, 8 …