Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant CNS tumor of
children below 6 months of age. The majority of AT/RTs demonstrate genomic alterations in …

Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant embryonal central nervous
system tumor commonly affecting children< 3 years of age. It roughly constitutes 1%–2% of …

Background Radiation therapy is the most commonly used postsurgical treatment for primary
malignant brain tumors. Consequently, investigating the efficacy of chemotherapeutics …

Purpose Atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system is a rare
cancer primarily affecting children younger than 5 years old. Because patients are young …

Atypical teratoid rhabdoid tumour (ATRT) is a malignant tumour of the central nervous
system with a dismal prognosis. There is no consensus on optimal treatment and different …

Radiotherapy plays an important role in the management of childhood cancer, with the
primary aim of achieving the highest likelihood of cure with the lowest risk of radiation …

Radiotherapy is an integral and highly effective aspect of the management of many
paediatric CNS tumours, including embryonal tumours, astrocytic tumours and ependymal …

Introduction Atypical teratoid/rhabdoid tumor (AT/RT) is a highly aggressive embryonal CNS
neoplasm, characterized by inactivation of SMARCB1 (INI1) or rarely of SMARCA4 (BRG1) …

Background and purpose Brain tumours are the most frequent solid tumours in children and
the most frequent radiotherapy indications in paediatrics, with frequent late effects: cognitive …

This paper focuses on genetic counselling in Phelan-McDermid syndrome (PMS), a rare
neurodevelopmental disorder caused by a deletion 22q13. 3 or a pathogenic variant in …