Naked mole rat (NMR) is the long-lived and tumor-resistant rodent. NMRs possess multiple
adaptations that may contribute to longevity and cancer-resistance. However, whether …

It has been 20 years since the publication of Chemistry of Protein Conjugation and Cross-
Linking. During this period, great advances have been made in the area of cross-linking of …

Skin aging is an ineluctable process leading to the progressive loss of tissue integrity and is
characterized by various outcomes such as wrinkling and sagging. Researchers have …

DNA probes for the studies of damaged strand excision during the nucleotide excision repair
(NER) have been designed using the novel non-nucleosidic phosphoramidite reagents that …

Nucleotide excision repair (NER) is a multistep process of recognition and elimination of a
wide spectrum of damages that cause significant distortions in DNA structure, such as UV …

Long linear DNA analogs of nucleotide excision repair (NER) substrates have been
synthesized. They are 137-mer duplexes containing in their internal positions nucleotides …

Murine Krebs-2 tumor-initiating stem cells are known to natively internalize extracellular
double-stranded DNA fragments. Being internalized, these fragments interfere in the repair …

The living cell DNA is under permanent attack of a variety of exogenous and endogenous
damaging factors. Nucleotide excision repair (NER) is main pathway which removes a wide …

Актуальность работы. ДНК живых организмов постоянно подвергается модификациям,
возникающим в результате воздействия различных факторов. Для предотвращения их …

Изобретение относится к области биохимии и молекулярной биологии. Предложен
способ оценки активности системы эксцизионной репарации нуклеотидов …