Monocyte subtypes and the CCR2 chemokine receptor in cardiovascular disease

CN França, MCO Izar, MNS Hortêncio… - Clinical …, 2017 - portlandpress.com
Monocytes circulate in the blood and migrate to inflammatory tissues, but their functions can
be either detrimental or beneficial, depending on their phenotypes. In humans, classical …

[HTML][HTML] The Fra-1: Novel role in regulating extensive immune cell states and affecting inflammatory diseases

YY He, HF Zhou, L Chen, YT Wang, WL Xie… - Frontiers in …, 2022 - frontiersin.org
Fra-1 (Fos-related antigen1), a member of transcription factor activator protein (AP-1), plays
an important role in cell proliferation, apoptosis, differentiation, inflammation, oncogenesis …

[HTML][HTML] Dorsal skinfold chamber models in mice

J Schreiter, S Meyer, C Schmidt… - GMS Interdisciplinary …, 2017 - ncbi.nlm.nih.gov
Background/purpose: The use of dorsal skinfold chamber models has substantially
improved the understanding of micro-vascularisation in pathophysiology over the last eight …

Monocyte chemokine receptors as therapeutic targets in cardiovascular diseases

DB Germano, SB Oliveira, ALL Bachi, Y Juliano… - Immunology …, 2023 - Elsevier
Chemokine receptors are fundamental in many processes related to cardiovascular
diseases, such as monocyte migration to vessel walls, cell adhesion, and angiogenesis …

[HTML][HTML] Circulating monocytes serve as novel prognostic biomarker in pancreatic ductal adenocarcinoma patients

FJ Hansen, P David, M Akram, S Knoedler… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal
malignant diseases. The association of monocytes with worse outcomes has been …

Monocytes are recruited from venules during arteriogenesis in the murine spinotrapezius ligation model

AC Bruce, MR Kelly-Goss, JL Heuslein… - … , and vascular biology, 2014 - Am Heart Assoc
Objective—Chronic arterial occlusion results in arteriogenesis of collateral blood vessels.
This process has been shown to be dependent on the recruitment of growth-promoting …

Cytokines and immune responses in murine atherosclerosis

PJH Kusters, E Lutgens - Methods in Mouse Atherosclerosis, 2015 - Springer
Atherosclerosis is an inflammatory disease of the vessel wall characterized by activation of
the innate immune system, with macrophages as the main players, as well as the adaptive …

Sequential staining improves detection of CCR2 and CX3CR1 on monocytes when simultaneously evaluating CCR5 by multicolor flow cytometry

E Jalbert, CM Shikuma, LC Ndhlovu… - Cytometry Part …, 2013 - Wiley Online Library
Chemokines and their receptors play an essential role within the immune system by
dictating cellular migration. In vivo, receptor–ligand interactions rarely occur in isolation as …

[PDF][PDF] 急性心肌梗死患者外周血单个核细胞趋化因子受体2 基因表达及临床意义

陈立强, 王洋洋, 司艳辉, 梁洁玲, 李海珠, 李刚 - 实用老年医学, 2013 - sylnyx.com
目的研究急性心肌梗死(acute myocardial infarction, AMI) 患者外周血单个核细胞趋化因子受体
2 (chemokine receptor2, CCR2) 基因表达及其与疾病发生, 发展的关系. 方法分别采用半定量 …

Agresif periodontitis hastalarında monosit kemoatraktan protein (MCP)-1 ve CC kemokin reseptör-2 polimorfizmlerinin sıklığının ve bu polimorfizmin gen ekspresyonu …

Ş Coşkuner - 2013 - acikerisim.selcuk.edu.tr
Özet Monosit kemoatraktan protein (MCP)-1, CC kemokin reseptör 2 (CCR2) ile etkileşime
geçerek monosit/makrofajların enflamasyon alanına yönlendirilmesinde anahtar öneme …