Chronic pain exerts an enormous personal and economic burden, affecting more than 30%
of people worldwide according to some studies. Unlike acute pain, which carries survival …

Migraine is a complex condition in which genetic predisposition interacts with other
biological and environmental factors determining its course. A hyperresponsive brain cortex …

Over the past 20 years, clinical and preclinical studies point to the anterior cingulate cortex
(ACC) as a site of interest for several neurological and psychiatric conditions. The ACC …

Background This systematic review was designed to evaluate the presence of comorbid
conditions among patients with temporomandibular disorders (TMDs). Types of Studies …

Chronic musculoskeletal pain affects more than 20% of the population, leading to high
health care overload and huge spending. The prevalence is increasing and negatively …

Objective The objective of the study was to determine the associations of depression and
anxiety with chronic pain among US adults. Setting Nationally representative cross …

Chronic pain is a public health concern affecting over 100 million US adults. Because
chronic pain is multifactorial, it requires a biopsychosocial approach to understand how …

Stress has been consistently linked to negative impacts on physical and mental health. More
specifically, patients with chronic pain experience stress intolerance, which is an …

Introduction Knee osteoarthritis (OA) is the most common form of arthritis, which is a leading
cause of disability. Although no cure exists for knee OA, physical activity has been shown to …

Temporomandibular disorders (TMD) are a multifactorial condition associated with both
physical and psychological factors. Stress has been known to trigger or worsens TMD. We …