Profiling cell identity and tissue architecture with single-cell and spatial transcriptomics
Single-cell transcriptomics has broadened our understanding of cellular diversity and gene
expression dynamics in healthy and diseased tissues. Recently, spatial transcriptomics has …
expression dynamics in healthy and diseased tissues. Recently, spatial transcriptomics has …
[HTML][HTML] Pan-cancer proteogenomics connects oncogenic drivers to functional states
Cancer driver events refer to key genetic aberrations that drive oncogenesis; however, their
exact molecular mechanisms remain insufficiently understood. Here, our multi-omics pan …
exact molecular mechanisms remain insufficiently understood. Here, our multi-omics pan …
Spatial multiplexing and omics
Much like solving a game of Clue, understanding physiological mysteries involves
answering who, what, when and where. Multiomics approaches delve into cellular and …
answering who, what, when and where. Multiomics approaches delve into cellular and …
The unveiled Mosaic of Intra-Tumor Heterogeneity in Ovarian Cancer Through Spatial Transcriptomic Technologies: a systematic review
L Masatti, M Marchetti, S Pirrotta, G Spagnol… - Translational …, 2024 - Elsevier
Epithelial ovarian cancer is a significant global health issue among women. Diagnosis and
treatment pose challenges due to difficulties in predicting patient responses to therapy …
treatment pose challenges due to difficulties in predicting patient responses to therapy …