Sickle cell disease (SCD) is the most common monogenic disorder in sub-Saharan Africa
(SSA). Blood transfusion to increase the oxygen carrying capacity of blood is vital in the …

Background and objectives Previous studies of Sub-Saharan Africans show significant
alloimmunization to red blood cell (RBC) antigens, but country-specific data are limited …

Background. Transfusion of red blood cells (RBC) is an essential therapeutic tool in sickle
cell disease (SCD). Repeated RBC transfusions can cause alloimmunization which causes …

BACKGROUND The routine pretransfusion investigations in Southern Ghana involve only
ABO‐D blood group typing and ABO compatibility testing without screening for irregular red …

Abstract Background Sub‐Saharan African countries face the challenge of immunological
transfusion safety that puts many patients at risk of post‐transfusion hemolytic reactions. This …

Introduction The alloimmunization following blood transfusion can be life‐threatening. The
Rh alloantibodies are one of the most common causes contributing to alloimmunization. This …

Blood transfusion remains a mainstay of management for patients with sickle cell disease.
Transfusion in patients with sickle cell disease can result in the development of …

Abstract Background In Africa, SCD is the most common inherited hematological disease
with high mortality rate at age one to five years. This disease was discovered early in Sudan …

Introduction: Blood transfusion remains a mainstay therapy in sickle cell disease (SCD).
Transfusional therapy may be complicated by allo-immunisation due to exposure to foreign …

Background: Blood transfusions are a life-saving measure to replace blood lost through
severe bleeding or as a life-saving treatment for various hematological conditions. Blood …