Plasmodium knowlesi is a malaria parasite that is found in nature in long-tailed and pig-
tailed macaques. Naturally acquired human infections were thought to be extremely rare …

Increased efforts in antimalarial drug discovery are urgently needed. The goal must be to
develop safe and affordable new drugs to counter the spread of malaria parasites that are …

We introduce the Bayesian skyline plot, a new method for estimating past population
dynamics through time from a sample of molecular sequences without dependence on a …

Hereditary xerocytosis is thought to be a rare genetic condition characterized by red blood
cell (RBC) dehydration with mild hemolysis. RBC dehydration is linked to reduced …

Malaria elimination strategies require surveillance of the parasite population for genetic
changes that demand a public health response, such as new forms of drug resistance,. Here …

Human malaria affects the vast majority of the world's population with the Plasmodium
falciparum species causing the highest rates of morbidity and mortality. With no licensed …

Malaria is a major killer of children worldwide and the strongest known force for evolutionary
selection in the recent history of the human genome. The past decade has seen growing …

Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

The aim of this review was to use geographic information systems in combination with
historical maps to quantify the anthropogenic impact on the distribution of malaria in the 20th …

Many organisms that cause infectious diseases, particularly RNA viruses, mutate so rapidly
that their evolutionary and ecological behaviours are inextricably linked. Consequently …