Giant virus biology and diversity in the era of genome-resolved metagenomics
The discovery of giant viruses, with capsids as large as some bacteria, megabase-range
genomes and a variety of traits typically found only in cellular organisms, was one of the …
genomes and a variety of traits typically found only in cellular organisms, was one of the …
[HTML][HTML] Natural carbon fixation and advances in synthetic engineering for redesigning and creating new fixation pathways
Background Autotrophic carbon fixation is the primary route through which organic carbon
enters the biosphere, and it is a key step in the biogeochemical carbon cycle. The Calvin …
enters the biosphere, and it is a key step in the biogeochemical carbon cycle. The Calvin …
Virologs, viral mimicry, and virocell metabolism: the expanding scale of cellular functions encoded in the complex genomes of giant viruses
M Moniruzzaman, MP Erazo Garcia… - FEMS microbiology …, 2023 - academic.oup.com
The phylum Nucleocytoviricota includes the largest and most complex viruses known. These
“giant viruses” have a long evolutionary history that dates back to the early diversification of …
“giant viruses” have a long evolutionary history that dates back to the early diversification of …
Metabolic arsenal of giant viruses: Host hijack or self-use?
Viruses generally are defined as lacking the fundamental properties of living organisms in
that they do not harbor an energy metabolism system or protein synthesis machinery …
that they do not harbor an energy metabolism system or protein synthesis machinery …
Mitochondria and viral infection: advances and emerging battlefronts
M Sorouri, T Chang, DC Hancks - MBio, 2022 - Am Soc Microbiol
Mitochondria are dynamic organelles vital for energy production with now appreciated roles
in immune defense. During microbial infection, mitochondria serve as signaling hubs to …
in immune defense. During microbial infection, mitochondria serve as signaling hubs to …
Structure–function analysis of an ancient TsaD–TsaC–SUA5–TcdA modular enzyme reveals a prototype of tRNA t6A and ct6A synthetases
M Jin, Z Zhang, Z Yu, W Chen, X Wang… - Nucleic Acids …, 2023 - academic.oup.com
Abstract N 6-threonylcarbamoyladenosine (t6A) is a post-transcriptional modification found
uniquely at position 37 of tRNAs that decipher ANN-codons in the three domains of life …
uniquely at position 37 of tRNAs that decipher ANN-codons in the three domains of life …
Amoebae: hiding in plain sight: unappreciated hosts for the very large viruses
VF Queiroz, RAL Rodrigues… - Annual Review of …, 2022 - annualreviews.org
For decades, viruses have been isolated primarily from humans and other organisms.
Interestingly, one of the most complex sides of the virosphere was discovered using free …
Interestingly, one of the most complex sides of the virosphere was discovered using free …
Viral complexity
FO Aylward, M Moniruzzaman - Biomolecules, 2022 - mdpi.com
Although traditionally viewed as streamlined and simple, discoveries over the last century
have revealed that viruses can exhibit surprisingly complex physical structures, genomic …
have revealed that viruses can exhibit surprisingly complex physical structures, genomic …
PoRVA G9P [23] and G5P [7] infections differentially promote PEDV replication by reprogramming glutamine metabolism
H Liu, H Tian, P Hao, H Du, K Wang, Y Qiu, X Yin… - PLoS …, 2024 - journals.plos.org
PoRVA and PEDV coinfections are extremely common in clinical practice. Although
coinfections of PoRVA and PEDV are known to result in increased mortality, the underlying …
coinfections of PoRVA and PEDV are known to result in increased mortality, the underlying …
Giant viruses as a source of novel enzymes for biotechnological application
EG de Oliveira, JVRP Carvalho, BB Botelho… - Pathogens, 2022 - mdpi.com
The global demand for industrial enzymes has been increasing in recent years, and the
search for new sources of these biological products is intense, especially in microorganisms …
search for new sources of these biological products is intense, especially in microorganisms …